Rapid, simple, and efficient deprotection of benzyl/benzylidene protected carbohydrates by utilization of flow chemistry

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Ekholm FS, Mandity IM, Fulop F, Leino R
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Publication year: 2011
Journal: Tetrahedron Letters
Journal acronym: TETRAHEDRON LETT
Volume number: 52
Issue number: 16
Start page: 1839
End page: 1841
Number of pages: 3
ISSN: 0040-4039


Abstract

A rapid, simple, and efficient deprotection procedure for the deprotection of benzyl- and/or benzylidene protected carbohydrates is described utilizing a continuous flow hydrogenation reactor. The method tolerates both acid- and base sensitive functional groups. The high efficiency, simple work-up, and short reaction time should make this method appealing to researchers working in the fields of carbohydrate chemistry and total synthesis. (C) 2011 Elsevier Ltd. All rights reserved.


Keywords

Benzyl/benzylidene, Flow chemistry, Heterogenous catalysis, Protective groups

Last updated on 2019-14-12 at 04:01