Nuclear stress granules: the awakening of a sleeping beauty?

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Sandqvist A, Sistonen L
Förläggare: ROCKEFELLER UNIV PRESS
Publiceringsår: 2004
Tidskrift: Journal of Cell Biology
Tidskriftsakronym: J CELL BIOL
Volym: 164
Nummer: 1
Artikelns första sida, sidnummer: 15
Artikelns sista sida, sidnummer: 17
Antal sidor: 3
ISSN: 0021-9525
eISSN: 1540-8140


Abstrakt

Nuclear stress granules are subnuclear compartments that form in response to heat shock and other stress stimuli. Although many components of nuclear stress granules have been identified, including HSF1 and pre-mRNA processing factors, their function remains a mystery. A paper in this issue describes the stress-induced transcriptional activation of one of the nuclear stress granule target sites, a heterochromatic region that has been considered silent (jolly et al., 2004). These intriguing findings will certainly give the research of these structures a new twist.

Senast uppdaterad 2019-23-09 vid 06:07