Nuclear stress granules: the awakening of a sleeping beauty?

A1 Journal article (refereed)

Internal Authors/Editors

Publication Details

List of Authors: Sandqvist A, Sistonen L
Publication year: 2004
Journal: Journal of Cell Biology
Journal acronym: J CELL BIOL
Volume number: 164
Issue number: 1
Start page: 15
End page: 17
Number of pages: 3
ISSN: 0021-9525
eISSN: 1540-8140


Nuclear stress granules are subnuclear compartments that form in response to heat shock and other stress stimuli. Although many components of nuclear stress granules have been identified, including HSF1 and pre-mRNA processing factors, their function remains a mystery. A paper in this issue describes the stress-induced transcriptional activation of one of the nuclear stress granule target sites, a heterochromatic region that has been considered silent (jolly et al., 2004). These intriguing findings will certainly give the research of these structures a new twist.

Last updated on 2019-20-10 at 05:09