Highly enantio- and diastereoselective one-pot reactions in aqueous media: Combined asymmetric Rh-catalyzed conjugate addition/metal-mediated allylation

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Kallstrom S, Jagt RBC, Sillanpaa R, Feringa BL, Minnaard AJ, Leino R
Publisher: WILEY-V C H VERLAG GMBH
Publication year: 2006
Journal: European Journal of Organic Chemistry
Journal acronym: EUR J ORG CHEM
Volume number: 2006
Issue number: 17
Start page: 3826
End page: 3833
Number of pages: 8
ISSN: 1434-193X


Abstract

1,3-Disubstituted, enantiopure cyclohexanols have been prepared in very high diastereoselectivities and good yields by a concise one-pot method combining the enantioselective rhodium-catalyzed conjugate addition of arylboronic acids with indium-mediated allylation into a highly efficient one-pot reaction in aqueous media. (c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006.


Keywords

allylation, asymmetric synthesis, conjugate addition, diastereoselectivity

Last updated on 2020-28-03 at 06:06