Global SUMOylation on active chromatin is an acute heat stress response restricting transcription

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Niskanen EA, Malinen M, Sutinen P, Toropainen S, Paakinaho V, Vihervaara A, Joutsen J, Kaikkonen MU, Sistonen L, Palvimo JJ
Publisher: BIOMED CENTRAL LTD
Publication year: 2015
Journal: GENOME BIOLOGY
Journal acronym: GENOME BIOL
Volume number: 16
Start page: 1
End page: 19
Number of pages: 19
ISSN: 1465-6906
eISSN: 1474-760X


Abstract

Conclusions: HS-triggered SUMOylation targets promoters and enhancers of actively transcribed genes where it restricts the transcriptional activity of the HS-induced genes. PIAS1-mediated promoter SUMOylation is likely to regulate Pol2-associated factors in HS.

Last updated on 2019-21-04 at 02:59