Immobilization of chiral ligands on polymer fibers by electron beam induced grafting and applications in enantioselective catalysis

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Degni S, Wilen CE, Leino R
Publisher: AMER CHEMICAL SOC
Publication year: 2001
Journal: Organic Letters
Journal acronym: ORG LETT
Volume number: 3
Issue number: 16
Start page: 2551
End page: 2554
Number of pages: 4
ISSN: 1523-7060


Abstract

Styrenic TADDOL and L-prolinol-derived monomers were immobilized on polyethylene fibers by electron beam induced preirradiation grafting using styrene as comonomer. The polymer-supported chiral ligands were utilized as catalysts in the asymmetric addition of diethylzinc to benzaldehyde. Fiber-bound titanium TADDOLate gave a quantitative conversion of benzaldehyde to 1-phenylpropan-1-ol in a 97:3 S/R enantiomeric ratio. The catalyst was successfully regenerated and employed in subsequent reactions with retention of high enantioselectivities.

Last updated on 2019-16-09 at 06:23