Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Izabela Redzynia, Natasza E. Ziólkowska, Wieslaw R. Majzner, Stefan Willför, Rainer Sjöholm, Patrik Eklund and Grzegorz Bujacz
Förläggare: MDPI AG
Publiceringsår: 2009
Tidskrift: Molecules
Tidskriftsakronym: MOLECULES
Volym: 14
Nummer: 10
Artikelns första sida, sidnummer: 4147
Artikelns sista sida, sidnummer: 4158
Antal sidor: 12
ISSN: 1420-3049


Abstrakt

X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction data for the dihydrokaempferol crystals were collected on a CAD4 diffractometer and on a synchrotron for the lariciresinol crystal. The investigated compounds inhibit lipid peroxidation and lariciresinol is additionally a good scavenger of superoxide radicals. The structural data presented in this work provide a useful basis for designing more active compounds with potential use as antioxidants.


Nyckelord

antioxidant potency, crystal structure, flavonoids, "host - guest" inclusion crystals, lignans, phenolic compounds

Senast uppdaterad 2019-20-10 vid 04:33