Cytotoxic activity of some glycoconjugates including saponins and anthracyclines

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Filip S. Ekholm, Ågnes Berényi, Lucas Lagerquist, Tiina Saloranta, István Zupkó, Gyula Schneider, János Wölfling, Reko Leino
Förläggare: ELSEVIER SCI LTD
Publiceringsår: 2012
Tidskrift: Carbohydrate Research
Tidskriftsakronym: CARBOHYD RES
Volym: 356
Artikelns första sida, sidnummer: 295
Artikelns sista sida, sidnummer: 298
Antal sidor: 4
ISSN: 0008-6215


Abstrakt

Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed. (C) 2012 Elsevier Ltd. All rights reserved.


Nyckelord

Anthracyclines, Cytotoxic activity, Glycoconjugates, Saponins

Senast uppdaterad 2019-15-12 vid 03:10