F-18-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer's disease

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Rokka J, Snellman A, Kaasalainen M, Salonen J, Zona C, La Ferla B, Nicotra F, Re F, Masserini M, Forsback S, Lopez-Picon F, Rinne JO, Haaparanta-Solin M, Solin O
Publisher: ELSEVIER SCIENCE BV
Publication year: 2016
Journal: European Journal of Pharmaceutical Sciences
Journal acronym: EUR J PHARM SCI
Volume number: 88
Start page: 257
End page: 266
Number of pages: 10
ISSN: 0928-0987


Abstract

Although the studied functionalized F-18-NLs were not suitable for PET imaging as such, the synthesis techniques introduced in this study can be utilized to modify the biological behavior of F-18-labeled NLs. (C) 2016 Elsevier B.V. All rights reserved.


Keywords

Alzheimer's disease, beta-amyloid plaques, Functionalized nanoliposomes, Nucleophilic 18F-fluorination, Positron emission tomography (PET)

Last updated on 2019-23-09 at 02:55