An approach to chemoenzymatic DKR of amines in Soxhlet apparatus

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Denys Mavrynsky, Reko Leino
Publisher: ELSEVIER SCIENCE SA
Publication year: 2014
Journal: Journal of Organometallic Chemistry
Journal acronym: J ORGANOMET CHEM
Volume number: 760
Start page: 161
End page: 166
Number of pages: 6
ISSN: 0022-328X


Abstract

The coexistence of thermolabile enzyme and metal catalyst for racemization of amines in chemoenzymatic dynamic kinetic resolution, requiring high temperature of operation, is enabled by carrying out the reaction in modified Soxhlet extraction system. Initial insights into the scope and limitations of the developed reaction system are discussed. (C) 2013 Elsevier B. V. All rights reserved.


Keywords

Chemoenzymatic synthesis, Chiral amines, DKR, Shvo's catalyst

Last updated on 2019-14-11 at 03:51