Synthesis of pharmaceutically active compounds containing a disubstituted piperidine framework

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Kallstrom S, Leino R
Förläggare: PERGAMON-ELSEVIER SCIENCE LTD
Publiceringsår: 2008
Tidskrift: Bioorganic and Medicinal Chemistry
Tidskriftsakronym: BIOORGAN MED CHEM
Volym: 16
Nummer: 2
Artikelns första sida, sidnummer: 601
Artikelns sista sida, sidnummer: 635
Antal sidor: 35
ISSN: 0968-0896


Abstrakt

The synthesis of pharmaceutically active compounds bearing a disubstituted piperidine framework is reviewed. Due to their frequent Occurrence in pharmaceutical research, functionalized piperidines and the synthetic methodologies used for their preparation are of considerable topical interest. The present review focuses on the synthetic pathways used for the preparation of disubstituted piperidines and also briefly covers the activity and/or usage of the same. (c) 2007 Elsevier Ltd. All rights reserved.

Senast uppdaterad 2020-26-05 vid 05:42