Synthesis of pharmaceutically active compounds containing a disubstituted piperidine framework

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Kallstrom S, Leino R
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Publication year: 2008
Journal: Bioorganic and Medicinal Chemistry
Journal acronym: BIOORGAN MED CHEM
Volume number: 16
Issue number: 2
Start page: 601
End page: 635
Number of pages: 35
ISSN: 0968-0896


Abstract

The synthesis of pharmaceutically active compounds bearing a disubstituted piperidine framework is reviewed. Due to their frequent Occurrence in pharmaceutical research, functionalized piperidines and the synthetic methodologies used for their preparation are of considerable topical interest. The present review focuses on the synthetic pathways used for the preparation of disubstituted piperidines and also briefly covers the activity and/or usage of the same. (c) 2007 Elsevier Ltd. All rights reserved.

Last updated on 2019-15-09 at 05:44