Electrospun TiO₂ nanofibers decorated Ti substrate for biomedical application

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Cristina Dumitriu, Andrei Bogdan Stoian, Irina Titorencu, Vasile Pruna, Victor V. Jinga, Rose-Marie Latonen, Johan Bobacka, Ioana Demetrescu
Publisher: Elsevier
Publication year: 2014
Journal: Materials Science and Engineering: C
Volume number: 45
Start page: 56
End page: 63
eISSN: 1873-0191


Abstract

Various TiO2 nanofibers on Ti surface have been fabricated via electrospinning and calcination. Due to different elaboration conditions the electrospun fibers have different surface feature morphologies, characterized by scanning electronic microscopy, surface roughness, and contact angle measurements. The results have indicated that the average sample diameters are between 32 and 44 nm, roughness between 61 and 416 nm, and all samples are hydrophilic. As biological evaluation, cell culture with MG63 cell line originally derived from a human osteosarcoma was performed and correlation between nanofibers elaboration, properties and cell response was established. The cell adherence and growth are more evident on Ti samples with more aligned fibers, higher roughness and strong hydrophilic character and such fibers have been elaborated with a high speed rotating cylinder collector, confirming the idea that nanostructure elaboration conditions guide the cells' growth.


Keywords

Cell growth, Electrospinning, Surface modification, TiO2 nanofiber

Last updated on 2019-14-11 at 04:05