Mesoporous silica nanoparticles in tissue engineering – a perspective

A2 Review article, Literature review, Systematic review


Internal Authors/Editors


Publication Details

List of Authors: Jessica Maria Rosenholm, Jixi Zhang, Mika Linden, Cecilia Sahlgren
Publisher: Future Medicine Ltd.
Publication year: 2016
Journal: Nanomedicine
Volume number: 11
Issue number: 4
Start page: 391
End page: 402
eISSN: 1748-6963


Abstract

In this review, we summarize the latest developments and give a perspective on future applications of mesoporous silica nanoparticles (MSNs) in regenerative medicine. MSNs constitute a flexible platform for controlled delivery of drugs and imaging agents in tissue engineering and stem cell therapy. We highlight the recent advances in applying MSNs for controlled drug delivery and stem cell tracking. We touch upon novel functions of MSNs in real time imaging of drug release and biological function, and as tools to control the chemical and mechanical environment of stem cells. We discuss the need for novel model systems for studying biofunctionality and biocompatibility of MSNs, and how the interdisciplinary activities within the field will advance biotechnology research.

Last updated on 2019-16-06 at 04:50