One-pot synthesis of pore-expanded hollow mesoporous silica particles

A1 Journal article (refereed)

Internal Authors/Editors

Publication Details

List of Authors: Didem Şen Karaman, Tina Gulin-Sarfraz, Jixi Zhang, Jessica M. Rosenholm
Publisher: Elsevier
Publication year: 2015
Journal: Materials Letters
Journal acronym: Mat. Lett.
Volume number: 143
Start page: 140
End page: 143
eISSN: 1873-4979


One-pot hard/soft template-free synthesis of hollow structured mesoporous silica particles (H-MSPs) with enlarged pore sizes was developed. By a simplified in situ hydrothermal treatment under mild conditions (70 °C), a hollow interior evolution to a final size of ~150 nm was successfully induced for the as-prepared particles from the sol–gel synthesis solution. The particles were evenly spherical with an average particle diameter of 350 nm, as well as a mean pore size of 5 nm in the mesoporous shell. Pore-swelling agents and aminosilane were demonstrated to contribute to the chemical irregularities in the silica network formation during particle growth, consequently leading to selective dissolution of the interior silica.


Drug delivery systems, porous materials, sol-gel

Last updated on 2019-17-10 at 02:53