Comparative safety evaluation of silica-based particles

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Kettiger H, Karaman DS, Schiesser L, Rosenholm JM, Huwyler J
Förläggare: Pergamon
Publiceringsår: 2015
Tidskrift: Toxicology in Vitro
Volym: 30
Nummer: 1
Artikelns första sida, sidnummer: 355
Artikelns sista sida, sidnummer: 363
ISSN: 0887-2333
eISSN: 1879-3177


Abstrakt

Silica nanoparticles (SNPs) are increasingly used as drug delivery systems (DDS) and for biomedical imaging. Therapeutic and diagnostic agents can be incorporated into the silica matrix to improve the stability and dissolution of drug substances in biological systems. However, the safety of SNPs as drug carriers remains controversial. To date, no validated and accepted nano-specific tests exist to predict the potentially harmful impact of these materials on the human body.

Senast uppdaterad 2019-22-08 vid 07:08