Synthesis and applications of diphosphine ligands derived from the lignan hydroxymatairesinol

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Yury Brusentsev, Patrik Eklund
Publiceringsår: 2015
Tidskrift: Catalysis Today
Volym: 241 Part B
Artikelns första sida, sidnummer: 260
Artikelns sista sida, sidnummer: 263


Abstrakt

Highly efficient methods for synthetic modifications of the natural lignan hydroxymatairesinol into chiral diphosphines similar to DIOP were developed. Catalytic activity and induction of enantioselectivity for the prepd. phosphines were evaluated in rhodium catalyzed hydrogenations of different functionalized alkenes. High catalytic activities were obsd. with low catalyst loading at atm. pressure. The phosphines showed moderate to high enantioselectivity depending on the substrate used. Hydrogenation of 1-​acetamidostyrene gave 84​% ee of the S-​enantiomer.


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Senast uppdaterad 2020-23-01 vid 03:46