Synthesis and applications of diphosphine ligands derived from the lignan hydroxymatairesinol

A1 Journal article (refereed)


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Publication Details

List of Authors: Yury Brusentsev, Patrik Eklund
Publication year: 2015
Journal: Catalysis Today
Volume number: 241 Part B
Start page: 260
End page: 263


Abstract

Highly efficient methods for synthetic modifications of the natural lignan hydroxymatairesinol into chiral diphosphines similar to DIOP were developed. Catalytic activity and induction of enantioselectivity for the prepd. phosphines were evaluated in rhodium catalyzed hydrogenations of different functionalized alkenes. High catalytic activities were obsd. with low catalyst loading at atm. pressure. The phosphines showed moderate to high enantioselectivity depending on the substrate used. Hydrogenation of 1-​acetamidostyrene gave 84​% ee of the S-​enantiomer.


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