Professor

Niklas Sandler

Vicerektor, Management
Email: niklas.sandler@abo.fi
Mobile: +358-469215883
Phone: +358-2-2154837


Professional interests

•Printing technologies in drug fabrication: 2D & 3D printing
•New drug carrier material research
•Cellulose-based particle engineering
•Solid state characterisation of drug substances, excipients, end-products
•Powder technology
•Quality control technologies for drug products


Research Areas


Peer-reviewed publications

A1 Journal article (refereed)
3D-Printed Isoniazid Tablets for the Treatment and Prevention of Tuberculosis—Personalized Dosing and Drug Release (2019)
Öblom Heidi, Zhang Jiaxiang, Pimparade Manjeet, Speer Isabell, Preis Maren, Repka Michael, Sandler Niklas
AAPS PharmSciTech
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A1 Journal article (refereed)
Vascularized 3D printed scaffolds for promoting bone regeneration (2019)
Yufei Yan, Hao Chen, Hongbo Zhang,Changjun Guo, Kai Yang, Kaizhe Chen, Ruoyu Cheng, Niandong Qian, Niklas Sandler, Yu Shrike Zhang, Haokai Shen, Jin Qi, Wenguo Cui, Lianfu Deng
Biomaterials
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A4 Conference proceedings
3D label free bio-transfer standards (2018)
Miikka Järvinen, Tuomas Vainikka , Tapani Viitala, Carlos Bermudez, Roger Artigas, Anton Nolvi, Pol Martinez, Niklas Sandler, Edward Hæggström, Ivan Kassamakov
Optical Metrology and Inspection for Industrial Applications V
SPIE
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A1 Journal article (refereed)
3D printed UV light cured polydimethylsiloxane devices for drug delivery (2018)
Holländer Jenny, Hakala Risto, Suominen Jaakko, Moritz Niko, Yliruusi Jouko, Sandler Niklas
International Journal of Pharmaceutics
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A1 Journal article (refereed)
Handheld colorimeter as quality control tool for inkjet printed flexible levothyroxine doses for pediatric use (2018)
Henrika Wickström, Anouk Broos, Johan O Nyman, Ewelina Kortesmäki, Patrik Eklund, Thomas de Beer, Maren Preis, Niklas Sandler
International Journal of Pharmaceutics
Elsevier
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A1 Journal article (refereed)
Investigation of dissolved cellulose in development of buccal discs for oromucosal drug delivery (2018)
Yildir Emrah, Sjöholm Erica, Preis Maren, Trivedi Poonam, Trygg Jani, Fardim Pedro, Sandler Niklas
Pharmaceutical Development and Technology
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A1 Journal article (refereed)
Novel biorenewable composite of wood polysaccharide and polylactic acid for three dimensional printing (2018)
Wenyang Xu, Andrey Pranovich, Peter Uppstu, Xiaoju Wang, Dennis Kronlund, Jarl Hemming, Heidi Öblom, Niko Moritz, Maren Preis, Niklas Sandler, Stefan Willför, Chunlin Xu
Carbohydrate Polymers
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A1 Journal article (refereed)
QR encoded smart oral dosage forms by inkjet printing (2018)
Edinger Magnus, Bar-Shalom Daniel, Sandler Niklas, Rantanen Jukka, Genina Natalja
International Journal of Pharmaceutics
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A2 Review article, Literature review, Systematic review
Three-dimensional printing of wood-derived biopolymers: A review focused on biomedical applications (2018)
Xu WY, Wang XJ, Sandler N, Willför S, Xu CL
ACS Sustainable Chemistry and Engineering
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A2 Review article, Literature review, Systematic review
3D printed drug delivery devices: perspectives and technical challenges (2017)
Palo M, Holländer J, Suominen J, Yliruusi J, Sandler N
Expert Review of Medical Devices
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A1 Journal article (refereed)
Application of a handheld NIR spectrometer in prediction of drug content in inkjet printed orodispersible formulations containing prednisolone and levothyroxine (2017)
Vakili H, Wickström H, Desai D, Preis M, Sandler N
International Journal of Pharmaceutics
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A1 Journal article (refereed)
Colorimetry as Quality Control Tool for Individual Inkjet-Printed Pediatric Formulations (2017)
Henrika Wickström, Johan O. Nyman, Mathias Indola, Heidi Sundelin, Leif Kronberg, Maren Preis, Jukka Rantanen, Niklas Sandler
AAPS PharmSciTech
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A1 Journal article (refereed)
Dehydration of nitrofurantoin monohydrate during melt extrusion (2017)
Raijada D, Arnfast L, Bond AD, Aho J, Bøtker J, Sandler N, Rantanen J
Crystal Growth and Design
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A1 Journal article (refereed)
Development of Oromucosal Dosage Forms by Combining Electrospinning and Inkjet Printing (2017)
Palo Mirja, Kogermann Karin, Laidmäe Ivo, Meos Andres, Preis Maren, Heinämäki Jyrki, Sandler Niklas
Molecular Pharmaceutics
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A1 Journal article (refereed)
Inkjet printing of antiviral PCL nanoparticles and anticancer cyclodextrin inclusion complexes on bioadhesive film for cervical administration (2017)
Varan C, Wickström H, Sandler N, Aktaş Y, Bilensoy E
International Journal of Pharmaceutics
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A1 Journal article (refereed)
Inkjet Printing of Drug-Loaded Mesoporous Silica Nanoparticles - A Platform for Drug Development (2017)
Wickström H, Hilgert E, Nyman JO, Desai D, Şen Karaman D, de Beer T, Sandler N, Rosenholm JM
Molecules
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A4 Conference proceedings
Round Robin test on bio-imaging transfer standard for 3D optical profilers (2017)
Nolvi A, Viitala T, Pérez AG, Sandler N, Hæggström E, Bermudez C, Artigas R, Kassamakov I
SPIE
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A2 Review article, Literature review, Systematic review
Tailored approaches in drug development and diagnostics: from molecular design to biological model systems (2017)
Cecilia Sahlgren, Annika Meinander, Hongbo Zhang, Fang Cheng, Maren Preis, Chunlin Xu, Tiina A. Salminen, Diana Toivola, Daniel Abankwa, Ari Rosling, Didem Şen Karaman, Outi M. H. Salo-Ahen, Ronald Österbacka, John E. Eriksson, Stefan Willför, Ion Petre, Jouko Peltonen, Reko Leino, Mark Johnson, Jessica Rosenholm, Niklas Sandler
Advanced Healthcare Materials
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A1 Journal article (refereed)
The effect of HPMC and MC as pore formers on the rheology of the implant microenvironment and the drug release in vitro (2017)
Aho J, Halme A, Boetker J, Water JJ, Bohr A, Sandler N, Rantanen J, Baldursdottir S
Carbohydrate Polymers
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A1 Journal article (refereed)
Application of a colorimetric technique in quality control for printed pediatric orodispersible drug delivery systems containing propranolol hydrochloride (2016)
Hossein Vakili, Johan O. Nyman, Natalja Genina, Maren Preis, Niklas Sandler
International Journal of Pharmaceutics
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A1 Journal article (refereed)
Ethylene vinyl acetate (EVA) as a new drug carrier for 3D printed medical drug delivery devices (2016)
Natalja Genina, Jenny Holländer, Harri Jukarainen, Ermei Mäkilä, Jarno Salonen, Niklas Sandler
European Journal of Pharmaceutical Sciences
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A1 Journal article (refereed)
Evaluation of inhaler handling-errors, inhaler perception and preference with Spiromax, Easyhaler and Turbuhaler devices among healthy Finnish volunteers: a single site, single visit crossover study (Finhaler) (2016)
Niklas Sandler, Jenny Holländer, Disa Långström, Pekka Santtila, Anni Saukkonen, Saku Torvinen
BMJ Open Respiratory Research
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A1 Journal article (refereed)
Perception of the Professional Knowledge of and Education on the Medical Technology Products among the Pharmacists in the Baltic and Nordic Countries—A Cross-Sectional Exploratory Study (2016)
Daisy Volmer, Aleksandra Sokirskaja, Raisa Laaksonen, Kirsti Vainio, Niklas Sandler, Kjell H Halvorsen, Reidun Lisbet Skeide Kjome, Sveinbjörn Gizurarson, Ruta Muceniece, Baiba Maurina, Jurgita Dauksiene, Lilian Ruuben, Ingunn Björnsdottir, Tagne Ratassepp, Jyrki Heinämäki
Pharmacy
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A2 Review article, Literature review, Systematic review
Printed Drug-Delivery Systems for Improved Patient Treatment (2016)
Niklas Sandler, Maren Preis
Trends in Pharmacological Sciences
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A1 Journal article (refereed)
Quantification of caffeine and loperamide in printed formulations by infrared spectroscopy (2016)
Mirja Palo, Karin Kogermann, Natalja Genina, Daniela Fors, Jouko Peltonen, Jyrki Heinämäki, Niklas Sandler
Journal of Drug Delivery Science and Technology
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A1 Journal article (refereed)
Three-dimensional printed PCL-based implantable prototypes of medical devices for controlled drug delivery (2016)
Jenny Holländer, Natalja Genina, Harri Jukarainen, Mohammad Khajeheian, Ari Rosling, Ermei Mäkilä, Niklas Sandler
Journal of Pharmaceutical Sciences
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A2 Review article, Literature review, Systematic review
Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review (2015)
Levente L. Simon, Hajnalka Pataki, György Marosi, Fabian Meemken, Konrad Hungerbühler, Alfons Baiker, Srinivas Tummala, Brian Glennon, Martin Kuentz, Gerry Steele, Herman J. M. Kramer, James W. Rydzak, Zengping Chen, Julian Morris, Francois Kjell, Ravendra Singh, Rafiqul Gani, Krist V. Gernaey, Marjatta Louhi-Kultanen, John O’Reilly, Niklas Sandler, Osmo Antikainen, Jouko Yliruusi, Patrick Frohberg, Joachim Ulrich, Richard D. Braatz, Tom Leyssens, Moritz von Stosch, Rui Oliveira, Reginald B. H. Tan, Huiquan Wu, Mansoor Khan, Des O’Grady, Anjan Pandey, Remko Westra, Emmanuel Delle-Case, Detlef Pape, Daniele Angelosante, Yannick Maret, Olivier Steiger, Miklós Lenner, Kaoutar Abbou-Oucherif, Zoltan K. Nagy, James D. Litster, Vamsi Krishna Kamaraju, Min-Sen Chiu
Organic Process Research and Development
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A1 Journal article (refereed)
Fabrication of drug-loaded edible carrier substrates from nanosuspensions by flexographic printing (2015)
Palo M, Kolakovic R, Laaksonen T, Määttänen A, Genina N, Salonen J, Peltonen J, Sandler N
International Journal of Pharmaceutics
A1 Journal article (refereed)
Hyperspectral imaging in quality control of inkjet printed personalised dosage forms (2015)
Hossein Vakili, Ruzica Kolakovic, Natalja Genina, Mathieu Marmion, Harri Salo, Petri Ihalainen, Jouko Peltonen, Niklas Sandler
International Journal of Pharmaceutics
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A1 Journal article (refereed)
Improvement of dissolution rate of indomethacin by inkjet printing (2015)
Henrika Wickström, Mirja Palo, Karen Rijckaert, Ruzica Kolakovic, Johan O. Nyman, Anni Määttänen, Petri Ihalainen, Jouko Peltonen, Natalja Genina, Thomas de Beer, Korbinian Löbmann, Thomas Rades, Niklas Sandler
European Journal of Pharmaceutical Sciences
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A1 Journal article (refereed)
Non-destructive assessment of mechanical properties of microcrystalline cellulose compacts (2015)
Emmi Palomäki, Henrik Ehlers, Osmo Antikainen, Niklas Sandler, Jouko Yliruusi
International Journal of Pharmaceutics
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A1 Journal article (refereed)
Perspective: Concepts of printing technologies for oral film formulations (2015)
Maren Preis, Joerg Breitkreutz, Niklas Sandler
International Journal of Pharmaceutics
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A2 Review article, Literature review, Systematic review
Printing technologies for biomolecule and cell-based applications (2015)
Petri Ihalainen, Anni Määttänen, Niklas Sandler
International Journal of Pharmaceutics
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A1 Journal article (refereed)
Processing of pharmaceutical materials by electrospraying under reduced pressure (2015)
Maija Nyström, Matti Murtomaa, Jorma Roine, Niklas Sandler, Jarno Salonen
Drug Development and Industrial Pharmacy
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A1 Journal article (refereed)
Solid-State Properties and Controlled Release of Ranitidine Hydrochloride from Tailored
Oxidised Cellulose Beads
(2015)
Jani Trygg, Emrah Yildir, Ruzica Kolakovic, Niklas Sandler, Pedro Fardim
Macromolecular Materials and Engineering
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A1 Journal article (refereed)
Three-Dimensional Printing of Drug-Eluting Implants: Preparation
of an Antimicrobial Polylactide Feedstock Material
(2015)
JORRIT JEROEN WATER, ADAM BOHR, JOHAN BOETKER, JOHANNA AHO, NIKLAS SANDLER, HANNE MØRCK NIELSEN, JUKKA RANTANEN
Journal of Pharmaceutical Sciences
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A1 Journal article (refereed)
Anionic cellulose beads for drug encapsulation and release (2014)
Trygg J, Yildir E, Kolakovic R, Sandler N, Fardim P
Cellulose
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A1 Journal article (refereed)
Designing Printable Medicinal Products: Solvent System and Carrier-Substrate Screening (2014)
Raijada D, Genina N, Fors D, Wisaeus E, Peltonen J, Rantanen J, Sandler N
Chemical Engineering and Technology
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A1 Journal article (refereed)
Future trends in drug formulation development and pharmaceutical manufacturing (2014)
Sandler Niklas
Dosis
A1 Journal article (refereed)
Influence of raw material properties upon critical quality attributes of continuously produced granules and tablets (2014)
Fonteyne M, Wickström H, Peeters E, Vercruysse J, Ehlers H, Peters BH, Remon JP, Vervaet C, Ketolainen J, Sandler N, Rantanen J, Naelapää K, De Beer T
European Journal of Pharmaceutics and Biopharmaceutics
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A1 Journal article (refereed)
Inhibitory Activity of the Isoflavone Biochanin A on Intracellular Bacteria of Genus Chlamydia and Initial Development of a Buccal Formulation. (2014)
Leena Hanski, Natalja Genina, Hanna Uvell, Kristina Malinovskaja, Åsa
Gylfe, Timo Laaksonen, Ruzica Kolakovic, Ermei Mäkilä, Jarno Salonen,
Jouni Hirvonen, Mikael Elofsson, Niklas Sandler, Pia M. Vuorela

PLoS ONE
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A1 Journal article (refereed)
Inkjet printing of Chitlac-nanosilver—a method to create functional coatings for non-metallic bone implants (2014)
Sara Nganga, Niko Moritz, Ruzica Kolakovic, Kristina Jakobsson, Johan O Nyman, Massimiliano Borgogna, Andrea Travan, Matteo Crosera, Ivan Donati, Pekka K Vallittu, Niklas Sandler
Biofabrication
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A1 Journal article (refereed)
On-line monitoring of fluid bed granulation by photometric imaging (2014)
Ira Soppela, Osmo Antikainen, Niklas Sandler, Jouko Yliruusi
European Journal of Pharmaceutics and Biopharmaceutics
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A1 Journal article (refereed)
Rapid interferometric imaging of printed drug laden multilayer structures (2014)
Sandler N, Kassamakov I, Ehlers H, Genina N, Ylitalo T, Haeggstrom E
Scientific Reports
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A1 Journal article (refereed)
Towards fabrication of 3D printed medical devices to prevent biofilm formation (2014)
Niklas Sandler, Ida Salmela, Adyary Fallarero, Ari Rosling, Mohammad Khajeheian, Ruzica Kolakovic, Natalja Genina, Johan Nyman, Pia Vuorela
International Journal of Pharmaceutics
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A1 Journal article (refereed)
Behavior of printable formulations of loperamide and caffeine on different substrates-Effect of print density in inkjet printing (2013)
Genina N, Fors D, Palo M, Peltonen J, Sandler N
International Journal of Pharmaceutics
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A4 Conference proceedings
Fabrication of printed drug-delivery systems (2013)
Natalja Genina, Ruzica Kolakovic, Mirja Palo, Daniela Fors, Helka Juvonen, Petri Ihalainen, Jouko Peltonen, Niklas Sandler
Society for Imaging Science and Technology
A1 Journal article (refereed)
Tailored beads made of dissolved cellulose—investigation of their drug release properties (2013)
Emrah Yildir, Ruzica Kolakovic, Natalja Genina, Jani Trygg, Martin Gericke, Leena Hanski, Henrik Ehlers, Jukka Rantanen, Mikko Tenho, Pia Vuorela, Pedro Fardim, Niklas Sandler
International Journal of Pharmaceutics
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Other publications

O2 Other
Thin Substrates manufactured by means of 3D-printing for tailor-made drug delivery systems (2016)
Heidi Öblom, Jannica Berg, Ida Alanko, Maren Preis, Niklas Sandler
International Journal of Pharmaceutics


Other Research Activities


Last updated on 2018-19-09 at 19:49