Lea Sistonen

Professor, Cellbiologi
E-post: lea.sistonen@abo.fi
Mobiltelefon: +358-504013513
Telefon: +358-2-2153311


Referentgranskade publikationer

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Frizzled-8 integrates Wnt-11 and transforminggrowth factor-βsignaling in prostate cancer (2018)
Virginia Murillo-Garzón, Irantzu Gorroño-Etxebarria, Malin Åkerfelt, Mikael Christer Puustinen, Lea Sistonen, Matthias Nees, James Carton, Jonathan Waxman, Robert M. Kypta
Nature Communications
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation (2018)
Kijima Toshiki, Prince Thomas L., Tigue Megan L., Yim Kendrick H., Schwartz Harvey, Beebe Kristin, Lee Sunmin, Budzynski Marek A., Williams Heinric, Trepel Jane B., Sistonen Lea, Calderwood Stuart, Neckers Len
Scientific Reports
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Sumoylation of Notch1 represses its target gene expression during cell stress (2018)
Christian JM Antila, Vilma Rraklli, Henri A Blomster, Käthe M Dahlström, Tiina A Salminen, Johan Holmberg, Lea Sistonen, Cecilia Sahlgren
Cell Death and Differentiation
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Chaperone co-inducer BGP-15 inhibits histone deacetylases and enhances the heat shock response through increased chromatin accessibility (2017)
Budzynski Marek A., Crul Tim, Himanen Samu, Toth Noemi, Otvos Ferenc, Sistonen Lea, Vigh Laszlo
Cell Stress and Chaperones
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Transcriptional response to stress is pre-wired by promoter and enhancer architecture (2017)
Vihervaara A, Mahat DB, Guertin MJ, Chu TY, Danko CG, Lis JT, Sistonen L
Nature Communications
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A2 Granskningsartikel, litteraturgranskning, systematisk granskning
Versatile Functions of Heat Shock Factors: It is Not All About Stress (2017)
Budzyński Marek Andrzej, Sistonen Lea
Current Immunology Reviews
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins (2016)
Karvinen S, Silvennoinen M, Vainio P, Sistonen L, Koch LG, Britton SL, Kainulainen H
Experimental Gerontology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors (2016)
Jaeger AM, Pemble CW, Sistonen L, Thiele DJ
Nature Structural and Molecular Biology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Cellular stress response cross talk maintains protein and energy homeostasis (2015)
Cynthia L Swan, Lea Sistonen
EMBO Journal
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Global SUMOylation on active chromatin is an acute heat stress response restricting transcription (2015)
Niskanen EA, Malinen M, Sutinen P, Toropainen S, Paakinaho V, Vihervaara A, Joutsen J, Kaikkonen MU, Sistonen L, Palvimo JJ
GENOME BIOLOGY
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Heat-shock factor 2 is a suppressor of prostate cancer invasion (2015)
Björk JK, Åkerfelt M, Joutsen J, Puustinen MC, Cheng F, Sistonen L, Nees M
Oncogene
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation (2015)
Budzynski MA, Puustinen MC, Joutsen J, Sistonen L
Molecular and Cellular Biology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival (2014)
Alexandra N. Elsing, Camilla Aspelin, Johanna K. Björk, Heidi A. Bergman, Samu V. Himanen, Marko J. Kallio, Pia Roos-Mattjus, Lea Sistonen
Journal of Cell Biology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Heat shock in the springtime (2014)
Kevin A. Morano, Lea Sistonen, Valérie Mezger
Cell Stress and Chaperones
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
HSF1 at a glance (2014)
Vihervaara A, Sistonen L
Journal of Cell Science
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Opposing effects of heat shock factors 1 and 2 on prostate cancer invasion (2013)
Åkerfelt M, Björk J, Mirtti T, Fey V, Sistonen L, Nees M
Cancer Research
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Role of HSF1 phopshorylation in heat shock response (2013)
Budzynski MA, Puustien M, Joutsen J, Anckar J, Sistonen L
FASEB Journal
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells (2013)
Vihervaara A, Sergelius C, Vasara J, Blom MAH, Elsing AN, Roos-Mattjus P, Sistonen L
Proceedings of the National Academy of Sciences
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Protein Inhibitor of Activated STAT3 (PIAS3) Protein Promotes SUMOylation and Nuclear Sequestration of the Intracellular Domain of ErbB4 Protein (2012)
Sundvall M, Korhonen A, Vaparanta K, Anckar J, Halkilahti K, Salah Z, Aqeilan RI, Palvimo JJ, Sistonen L, Elenius K
Journal of Biological Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
A simple mass-action model for the eukaryotic heat shock response and its mathematical validation (2011)
Petre I, Mizera A, Hyder CL, Meinander A, Mikhailov A, Morimoto RI, Sistonen L, Eriksson JE, Back RJ
Natural Computing
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A2 Granskningsartikel, litteraturgranskning, systematisk granskning
Regulation of HSF1 Function in the Heat Stress Response: Implications in Aging and Disease (2011)
Anckar J, Sistonen L
Annual Review of Biochemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Anaphase-Promoting Complex/Cyclosome Participates in the Acute Response to Protein-Damaging Stress (2010)
Ahlskog JK, Björk JK, Elsing AN, Aspelin C, Kallio M, Roos-Mattjus P, Sistonen L
Molecular and Cellular Biology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
APC/C plays a role in the acute response to protein-damaging stress (2010)
Roos-Mattjus P, Ahlskog JK, Björk JK, Elsing AN, Kallio M, Sistonen L
EJC Supplements
A2 Granskningsartikel, litteraturgranskning, systematisk granskning
Heat shock factors: integrators of cell stress, development and lifespan (2010)
Åkerfelt M, Morimoto RI, Sistonen L
Nature Reviews Molecular Cell Biology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Heat Shock Transcription Factor 1 Localizes to Sex Chromatin during Meiotic Repression (2010)
Åkerfelt M, Vihervaara A, Laiho A, Conter A, Christians ES, Sistonen L, Henriksson E
Journal of Biological Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification (2010)
Blomster, Imanishi, Siimes, Kastu, Morrice, Eriksson, Sistonen
Journal of Biological Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
miR-18, a member of Oncomir-1, targets heat shock transcription factor 2 in spermatogenesis (2010)
Björk JK, Sandqvist A, Elsing AN, Kotaja N, Sistonen L
Development
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Regulation of the members of the mammalian heat shock factor family (2010)
Björk JK, Sistonen L
FEBS Journal
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A3 Bokavsnitt, kapitel i forskningsböcker
A New Mathematical Model for the Heat Shock Response (2009)
Petre I, Mizera A, Hyder CL, Mikhailov A, Eriksson JE, Sistonen L, Back RJ
Springer
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Heterotrimerization of Heat-Shock Factors 1 and 2 Provides a Transcriptional Switch in Response to Distinct Stimuli (2009)
Sandqvist A, Björk JK, Åkerfelt M, Chitikova Z, Grichine A, Vourch C, Jolly C, Salminen TA, Nymalm Y, Sistonen L
Molecular Biology of the Cell
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Mammalian Heat Shock Factor 1 Is Essential for Oocyte Meiosis and Directly Regulates Hsp90 Expression (2009)
Metchat A, Åkerfelt M, Bierkamp C, Delsinne V, Sistonen L, Alexandre H, Christians ES
Journal of Biological Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Novel Proteomics Strategy Brings Insight into the Prevalence of SUMO-2 Target Sites (2009)
Blomster HA, Hietakangas V, Wu JM, Kouvonen P, Hautaniemi S, Sistonen L
Molecular and Cellular Proteomics
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
PROMOTER CHIP-CHIP ANALYSIS IN MOUSE TESTIS REVEALS Y CHROMOSOME OCCUPANCY BY HSF1 AND HSF2 (2009)
Henriksson E, Akerfelt M, Vihervaara A, Kotaja N, Sistonen L, Laiho A, Rautoma K
Journal of Andrology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Restoring Proteostasis via Chaperone Networks in Ageing and Neurodegenerative Disease (2009)
Morimoto R, Prahlad V, Ben-Zvi A, Gidalevitz T, Westerheide S, Anckar J, Sistonen L, Guisbert E, Czyz D, Voisine C, Silva C, Beam M
FASEB Journal
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1 (2009)
Westerheide SD, Anckar J, Stevens SM, Sistonen L, Morimoto RI
Science
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
TransLISA, a novel quantitative, nonradioactive assay for transcription factor DNA-binding analyses (2009)
Vuori KA, Ahlskog JK, Sistonen L, Nikinmaa M
FEBS Journal
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Promoter ChIP-chip analysis in mouse testis reveals Y chromosome occupancy by HSF2 (2008)
Åkerfelt M, Henriksson E, Laiho A, Vihervaara A, Rautoma K, Kotaja N, Sistonen L
Proceedings of the National Academy of Sciences
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Evidence that the p38 MAP kinase pathway is dysregulated in HLA-B27-expressing human monocytic cells - Correlation with HLA-B27 misfolding (2007)
Sahlberg AS, Penttinen MA, Heiskanen KM, Colbert RA, Sistonen L, Granfors K
Arthritis and Rheumatism
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Fever-like hyperthermia controls T Lymphocyte persistence by inducing degradation of cellular FLIPshort (2007)
Meinander, Söderström, Kaunisto, Poukkula, Sistonen, Eriksson
Journal of Immunology
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A3 Bokavsnitt, kapitel i forskningsböcker
Heat shock factor 1 as a coordinator of stress and developmental pathways (2007)
Anckar J, Sistonen L
Springer
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Heat shock factor 2 (HSF2) contributes to inducible expression of hsp genes through interplay with HSF1 (2007)
Östling P, Björk JK, Roos-Mattjus P, Mezger V, Sistonen L
Journal of Biological Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Heat shock factors at a crossroad between stress and development (2007)
Åkerfelt M, Trouillet D, Mezger V, Sistonen L
Annals of the New York Academy of Sciences
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Hyperfluidization-coupled membrane microdomain reorganization is linked to activation of the heat shock response in a murine melanoma cell line (2007)
Nagy E, Balogi Z, Gombos I, Åkerfelt M, Björkbom A, Balogh G, Török Z, Maslyanko A, Fiszer-Kierzkowska A, Lisowska K, Slotte PJ, Sistonen L, Horvath I, Vigh L
Proceedings of the National Academy of Sciences
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Inhibition of DNA binding by differential sumoylation of heat shock factors (2006)
Anckar J, Hietakangas V, Denessiouk K, Thiele DJ, Johnson MS, Sistonen L
Molecular and Cellular Biology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
PDSM, a motif for phosphorylation-dependent SUMO modification (2006)
Hietakangas V, Anckar J, Blomster HA, Fujimoto M, Palvimo JJ, Nakai A, Sistonen L
Proceedings of the National Academy of Sciences
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression (2006)
Chang YH, Östling P, Åkerfelt M, Trouillet D, Rallu M, Gitton Y, El Fatimy R, Fardeau V, Le Crom S, Morange M, Sistonen L, Mezger V
Genes and Development
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
CD95-mediated alteration in Hsp70 levels is dependent on protein stabilization (2005)
Concannon CG, FitzGerald U, Holmberg CI, Szegezdi E, Sistonen L, Samali A
Cell Stress and Chaperones
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Rapid turnover of c-FLIPshort is determined by its unique C-terminal tail (2005)
Poukkula, Kaunisto, Hietakangas, Denessiouk, Katajamäki, Johnson, Sistonen, Eriksson
Journal of Biological Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Enhanced intracellular replication of Salmonella enteritidis in HLA-B27-expressing human monocytic cells - Dependency on glutamic acid at position 45 in the B pocket of HLA-B27 (2004)
Penttinen MA, Heiskanen KM, Mohapatra R, DeLay ML, Colbert RA, Sistonen L, Granfors K
Arthritis and Rheumatism
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Nuclear stress granules: the awakening of a sleeping beauty? (2004)
Sandqvist A, Sistonen L
Journal of Cell Biology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
The ubiquitin-proteasome pathway (2004)
Roos-Mattjus P, Sistonen L
Annals of Medicine
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Erythroid differentiation sensitizes K562 leukemia cells to TRAIL-induced apoptosis by downregulation of c-FLIP (2003)
Hietakangas V, Poukkula M, Heiskanen KM, Karvinen JT, Sistonen L, Eriksson JE
Molecular and Cellular Biology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Formation of nuclear stress granules involves HSF2 and coincides with the nucleolar localization of Hsp70 (2003)
Alastalo TP, Hellesuo M, Sandqvist A, Hietakangas V, Kallio M, Sistonen L
Journal of Cell Science
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis (2003)
Tran SEF, Meinander A, Holmström TH, Rivero-Muller A, Heiskanen KM, Linnau EK, Courtney MJ, Mosser DD, Sistonen L, Eriksson JE
Cell Death and Differentiation
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1 (2003)
Hietakangas V, Ahlskog JK, Jakobsson AM, Hellesuo M, Sahlberg NM, Holmberg CI, Mikhailov A, Palvimo JJ, Pirkkala L, Sistonen L
Molecular and Cellular Biology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice (2002)
Kallio M, Chang YH, Manuel M, Alastalo TP, Rallu M, Gitton Y, Pirkkala L, Loones MT, Paslaru L, Larney S, Hiard S, Morange M, Sistonen L, Mezger V
EMBO Journal
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
HLA-B27 modulates nuclear factor kappa B activation in human monocytic cells exposed to liplopolysaccharide (2002)
Penttinen MA, Holmberg CI, Sistonen L, Granfors K
Arthritis and Rheumatism
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Multisite phosphorylation provides sophisticated regulation of transcription factors (2002)
Holmberg CI, Tran SEF, Eriksson JE, Sistonen L
Trends in Biochemical Sciences
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Neuronal cells show regulatory differences in the hsp70 gene response (2002)
Kaarniranta K, Oksala N, Karjalainen HM, Suuronen T, Sistonen L, Helminen HJ, Salminen A, Lammi MJ
Molecular Brain Research
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Reperfusion but not acute ischemia in pig small intestine induces transcriptionally mediated heat shock response in situ (2002)
Oksala NKJ, Kaarniranta K, Tenhunen JJ, Tiihonen R, Heino A, Sistonen L, Paimela H, Alhava E
European Surgical Research
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Activation of the MKK4-JNK pathway during erythroid differentiation of K562 cells is inhibited by the heat shock factor 2-beta isoform (2001)
Hietakangas, Elo, Rosenström, Coffey, Kyriakis, Eriksson, Sistonen
FEBS Letters
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Characterization of a hypoxia-inducible factor (HIF-1 alpha) from rainbow trout - Accumulation of protein occurs at normal venous oxygen tension (2001)
Soitamo AJ, Råbergh CMI, Gassmann M, Sistonen L, Nikinmaa M
Journal of Biological Chemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Differential induction of Hsp70-encoding genes in human hematopoietic cells (2001)
Leppä S, Kajanne R, Arminen L, Sistonen L
Journal of Biological Chemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Genomic organization and promoter analysis of the human heat shock factor 2 gene (2001)
Nykänen P, Alastalo TP, Ahlskog J, Horelli-Kuitunen N, Pirkkala L, Sistonen L
Cell Stress and Chaperones
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1 (2001)
Holmberg, Hietakangas, Mikhailov, Rantanen, Kallio, Meinander, Hellman, Morrice, MacKintosh, Morimoto, Eriksson, Sistonen
EMBO Journal
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Primary chondrocytes resist hydrostatic pressure-induced stress while primary synovial cells and fibroblasts show modified Hsp70 response (2001)
Kaarniranta, Holmberg, Lammi, Eriksson, Sistonen, Helminen
Osteoarthritis and Cartilage
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond (2001)
Pirkkala L, Nykänen P, Sistonen L
FASEB Journal
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway (2000)
Pirkkala L, Alastalo TP, Zuo X, Benjamin IJ, Sistonen L
Molecular and Cellular Biology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Formation of nuclear HSF1 granules varies depending on stress stimuli (2000)
Holmberg CI, Illman SA, Kallio M, Mikhailov A, Sistonen L
Cell Stress and Chaperones
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Heat-shocked A20 lymphoma cells fail to induce degranulation of cytotoxic T lymphocytes: Possible mechanism of resistance (2000)
Jackson KM, DeLeon M, Sistonen L, Verret CR
Cellular Immunology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Heat shock factor 2 is activated during mouse heart development (2000)
Eriksson M, Jokinen E, Sistonen L, Leppä S
International Journal of Developmental Biology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Protein synthesis is required for stabilization of hsp70 mRNA upon exposure to both hydrostatic pressurization and elevated temperature (2000)
Kaarniranta, Holmberg, Helminen, Eriksson, Sistonen, Lammi
FEBS Letters
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Tissue-specific expression of zebrafish (Danio rerio) heat shock factor 1 mRNAS in response to heat stress (2000)
Rabergh CMI, Airaksinen S, Soitamo A, Bjorklund HV, Johansson T, Nikinmaa M, Sistonen L
Journal of Experimental Biology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Antibody supershift assay is inadequate for determining HSF stoichiometry in HSE complexes (1999)
Pirkkala L, Sistonen L
Cell Stress and Chaperones
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Differentiation lineage-specific expression of human heat shock transcription factor 2 (1999)
Pirkkala L, Alastalo TP, Nykänen P, Seppä L, Sistonen L
FASEB Journal
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Thermotolerance and cell death are distinct cellular responses to stress: dependence on heat shock proteins (1999)
Samali A, Holmberg CI, Sistonen L, Orrenius S
FEBS Letters
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Conventional and novel PKC isoenzymes modify the heat-induced stress response but are not activated by heat shock (1998)
Holmberg, Roos, Lord, Eriksson, Sistonen
Journal of Cell Science
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Effects of heat shock and hypoxia on protein synthesis in rainbow trout (Oncorhynchus mykiss) cells (1998)
Airaksinen S, Råbergh CM, Sistonen L, Nikinmaa M
Journal of Experimental Biology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation (1998)
Kaarniranta K, Elo M, Sironen R, Lammi MJ, Goldring MB, Eriksson JE, Sistonen L, Helminen HJ
Proceedings of the National Academy of Sciences
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Stage-specific expression and cellular localization of the heat shock factor 2 isoforms in the rat seminiferous epithelium (1998)
Alastalo TP, Lönnström M, Leppä S, Kaarniranta K, Pelto-Huikko M, Sistonen L, Parvinen M
Experimental Cell Research
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Suppression of Fas/APO-1-mediated apoptosis by mitogen-activated kinase signaling (1998)
Holmström, Chow, Elo, Coffey, Orrenius, Sistonen, Eriksson
Journal of Immunology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Heat shock response - Pathophysiological implications (1997)
Leppa S, Sistonen L
Annals of Medicine
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Overexpression of HSF2-beta inhibits hemin-induced heat shock gene expression and erythroid differentiation in K562 cells (1997)
Leppä S, Pirkkala L, Saarento H, Sarge KD, Sistonen L
Journal of Biological Chemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
The phorbol ester 12-O-tetradecanoylphorbol 13-acetate enhances the heat-induced stress response (1997)
Holmberg, Leppä, Eriksson, Sistonen
Journal of Biological Chemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Thioredoxin is transcriptionally induced upon activation of heat shock factor 2 (1997)
Leppä, Pirkkala, Chow, Eriksson, Sistonen
Journal of Biological Chemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
CELL-TRANSFORMATION BY C-HA-RAS(VAL12) ONCOGENE IS ACCOMPANIED BY A DECREASE IN HISTONE H1-DEGREES AND AN INCREASE IN NUCLEOSOMAL REPEAT LENGTH (1995)
LAITINEN J, SISTONEN L, ALITALO K, HÖLTTÄ E
Journal of Cellular Biochemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
METAL REGULATION OF HEAT-SHOCK FACTOR ACTIVITY (1995)
MORIMOTO RI, KLINE M, MATHEW A, MATHUR S, SATYAL S, SHI YH, SISTONEN L
Journal of Cellular Biochemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
PHOSPHORYLATION-MEDIATED SIGNALING MECHANISMS AFFECT THE DNA-BINDING ACTIVITY OF HEAT-SHOCK TRANSCRIPTION FACTOR-1 IN K562 CELLS (1995)
HOLMBERG CI, ERIKSSON JE, SISTONEN L
Molecular Biology of the Cell
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
ARACHIDONATE IS A POTENT MODULATOR OF HUMAN HEAT-SHOCK GENE-TRANSCRIPTION (1994)
JURIVICH DA, SISTONEN L, SARGE KD, MORIMOTO RI
Proceedings of the National Academy of Sciences
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
DEFICIENT INDUCTION OF HUMAN HSP70 HEAT-SHOCK GENE-TRANSCRIPTION IN Y79 RETINOBLASTOMA CELLS DESPITE ACTIVATION OF HEAT-SHOCK FACTOR-1 (1994)
MATHUR SK, SISTONEN L, BROWN IR, MURPHY SP, SARGE KD, MORIMOTO RI
Proceedings of the National Academy of Sciences
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
HUMAN HEAT-SHOCK FACTORS 1 AND 2 ARE DIFFERENTIALLY ACTIVATED AND CAN SYNERGISTICALLY INDUCE HSP70 GENE-TRANSCRIPTION (1994)
SISTONEN L, SARGE KD, MORIMOTO RI
Molecular and Cellular Biology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
STRESS INDUCTION OF THE MAMMALIAN GRP78/BIP PROTEIN GENE - IN-VIVO GENOMIC FOOTPRINTING AND IDENTIFICATION OF P70CORE FROM HUMAN NUCLEAR EXTRACT AS A DNA-BINDING COMPONENT SPECIFIC TO THE STRESS REGULATORY ELEMENT (1994)
LI WW, SISTONEN L, MORIMOTO RI, LEE AS
Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
CA2+ AND ZN2+ DEPENDENCE OF DNA-SYNTHESIS IN UNTRANSFORMED AND IN HA-RAS(VAL-12)-EXPRESSING NIH-3T3 CELLS (1993)
BACK CJ, SISTONEN L, ENKVIST MOK, HEIKKILÄ JE, ÅKERMAN KEO
Experimental Cell Research
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
ACTIVATION OF HEAT-SHOCK FACTOR-II DURING HEMIN-INDUCED DIFFERENTIATION OF HUMAN ERYTHROLEUKEMIA CELLS (1992)
SISTONEN L, SARGE KD, PHILLIPS B, ABRAVAYA K, MORIMOTO RI
Molecular and Cellular Biology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
ANALYSIS OF TYROSINE KINASE MESSENGER-RNAS INCLUDING 4 FGF RECEPTOR MESSENGER-RNAS EXPRESSED IN MCF-7 BREAST-CANCER CELLS (1992)
LEHTOLA L, PARTANEN J, SISTONEN L, KORHONEN J, WARRI A, HARKONEN P, CLARKE R, ALITALO K
International Journal of Cancer
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
ANTIPROLIFERATIVE PROSTAGLANDINS ACTIVATE HEAT-SHOCK TRANSCRIPTION FACTOR (1992)
AMICI C, SISTONEN L, SANTORO MG, MORIMOTO RI
Proceedings of the National Academy of Sciences
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
EFFECT OF SODIUM SALICYLATE ON THE HUMAN HEAT SHOCK RESPONSE (1992)
JURIVICH DA, SISTONEN L, KROES RA, MORIMOTO RI
Science
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
CONSTITUTIVELY ACTIVATED NEU ONCOPROTEIN TYROSINE KINASE INTERFERES WITH GROWTH FACTOR-INDUCED SIGNALS FOR GENE ACTIVATION (1991)
LEHTOLA L, SISTONEN L, KOSKINEN P, LEHVÄSLAIHO H, DIRENZO MF, COMOGLIO PM, ALITALO K
Journal of Cellular Biochemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
NUCLEAR COLOCALIZATION OF CELLULAR AND VIRAL MYC PROTEINS WITH HSP70 IN MYC-OVEREXPRESSING CELLS (1991)
KOSKINEN PJ, SISTONEN L, EVAN G, MORIMOTO R, ALITALO K
Journal of Virology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
C-HA-RAS VAL-12 ONCOGENE-TRANSFORMED NIH-3T3 FIBROBLASTS DISPLAY MORE DECONDENSED NUCLEOSOMAL ORGANIZATION THAN NORMAL FIBROBLASTS (1990)
LAITINEN J, SISTONEN L, ALITALO K, HÖLTTÄ E
Journal of Cell Biology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
DOWN-REGULATION OF THE EARLY GENOMIC GROWTH-FACTOR RESPONSE IN NEU ONCOGENE-TRANSFORMED CELLS (1990)
SISTONEN L, KOSKINEN PJ, LEHVÄSLAIHO H, LEHTOLA L, BRAVO R, ALITALO K
Oncogene
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
INCREASED ERYTHROID POTENTIATING ACTIVITY/TISSUE INHIBITOR OF METALLOPROTEINASES AND JUN/FOS TRANSCRIPTION FACTOR COMPLEX CHARACTERIZE TUMOR PROMOTER-INDUCED MEGAKARYOBLASTIC DIFFERENTIATION OF K562 LEUKEMIA CELLS (1990)
ALITALO R, PARTANEN J, PERTOVAARA L, HOLTTA E, SISTONEN L, ANDERSSON L, ALITALO K
Blood
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
REGULATION BY EGF IS MAINTAINED IN AN OVEREXPRESSED CHIMERIC EGFR NEU RECEPTOR TYROSINE KINASE (1990)
LEHVäSLAIHO H, SISTONEN L, DIRENZO F, PARTANEN J, COMOGLIO P, HÖLTTÄ E, ALITALO K
Journal of Cellular Biochemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
REGULATION BY TGF-BETA OF GENES INVOLVED IN GROWTH-CONTROL INTERLEUKIN-6 (1990)
LOHI J, PERTOVAARA L, SISTONEN L, ALITALO K, KESKIOJA J
Annals of the New York Academy of Sciences
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
A CHIMERIC EGF-R-NEU PROTO-ONCOGENE ALLOWS EGF TO REGULATE NEU TYROSINE KINASE AND CELL-TRANSFORMATION (1989)
LEHVÄSLAIHO H, LEHTOLA L, SISTONEN L, ALITALO K
EMBO Journal
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
ACTIVATION OF THE NEU TYROSINE KINASE INDUCES THE FOS/JUN TRANSCRIPTION FACTOR COMPLEX, THE GLUCOSE TRANSPORTER, AND ORNITHINE DECARBOXYLASE (1989)
SISTONEN L, HÖLTTÄ E, LEHVÄSLAIHO H, LEHTOLA L, ALITALO K
Journal of Cell Biology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
DOWN-REGULATION OF PROTEOLYTIC ACTIVITY IN 12-O-TETRADECANOYL-PHORBOL-13-ACETATE-INDUCED K562 LEUKEMIA CELL CULTURES - DEPLETION OF ACTIVE UROKINASE BY EXCESS TYPE-1 PLASMINOGEN-ACTIVATOR INHIBITOR (1989)
ALITALO R, ANDERSSON LC, TAPIOVAARA H, SISTONEN L, VAHERI A, STEPHENS R
Journal of Cellular Physiology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
ENHANCED JUN GENE-EXPRESSION IS AN EARLY GENOMIC RESPONSE TO TRANSFORMING GROWTH FACTOR BETA STIMULATION (1989)
PERTOVAARA L, SISTONEN L, BOS TJ, VOGT PK, KESKIOJA J, ALITALO K
Molecular and Cellular Biology
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
MECHANISM OF T-CELL PROLIFERATION IN VIVO - ANALYSIS OF IL-2 RECEPTOR EXPRESSION AND ACTIVATION OF C-MYC AND C-MYB ONCOGENES DURING LYMPHATIC REGENERATION (1989)
SIHVOLA M, SISTONEN L, ALITALO K, HURME M
Biochemical and Biophysical Research Communications
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
THE CELLULAR-RESPONSE TO INDUCTION OF THE P21 C-HA-RAS ONCOPROTEIN INCLUDES STIMULATION OF JUN GENE-EXPRESSION (1989)
SISTONEN L, HÖLTTÄ E, MÄKELÄ TP, KESKIOJA J, ALITALO K
EMBO Journal
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
THE MECHANISMS OF ORNITHINE DECARBOXYLASE DEREGULATION IN C-HA-RAS ONCOGENE-TRANSFORMED NIH 3T3 CELLS (1988)
HÖLTTÄ E, SISTONEN L, ALITALO K
Journal of Biological Chemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
DOSE EFFECTS OF TRANSFECTED C-HA-RASVAL 12 ONCOGENE IN TRANSFORMED CELL CLONES (1987)
SISTONEN L, KESKIOJA J, ULMANEN I, HÖLTTÄ E, WIKGREN BJ, ALITALO K
Experimental Cell Research
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
MYC-ONCOGENES - ACTIVATION AND AMPLIFICATION (1987)
ALITALO K, KOSKINEN P, MÄKELÄ TP, SAKSELA K, SISTONEN L, WINQVIST R
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
ACTIVATION OF C-RAS ONCOGENES BY MUTATIONS AND AMPLIFICATION (1986)
SISTONEN L, ALITALO K
Annals of Clinical Research
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
EVIDENCE FOR COMMON PHARMACOLOGICAL PROPERTIES OF [H-3]5-HYDROXYTRYPTAMINE BINDING-SITES, PRE-SYNAPTIC 5-HYDROXYTRYPTAMINE AUTORECEPTORS IN CNS AND INHIBITORY PRE-SYNAPTIC 5-HYDROXYTRYPTAMINE RECEPTORS ON SYMPATHETIC-NERVES (1983)
ENGEL G, GOTHERT M, MULLERSCHWEINITZER E, SCHLICKER E, SISTONEN L, STADLER PA
Naunyn-Schmiedeberg's Archives of Pharmacology


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B1 Icke-referentgranskade tidskriftsartiklar
The VIII International Congress on Stress Proteins in Biology and Medicine: täynnä henkeä (2018)
Cristina Bonorino, Lea Sistonen, John Eriksson, Valérie Mezger, Gabriella Santoro, Lawrence E. Hightower
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Visa på utgivarens sida
D2 Artikel i en professionell bok
ORNITHINE DECARBOXYLASE GENE EXPRESSION IN NORMAL AND TRANSFORMED CELLS (1990)
HOLTTA E, SISTONEN L

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