Ph.D.

Thomas Nyholm

Senior Research Associate, Biochemistry
Email: thomas.nyholm@abo.fi


Peer-reviewed publications

A1 Journal article (refereed)
Impact of Acyl Chain Mismatch on the Formation and Properties of Sphingomyelin-Cholesterol Domains (2019)
Nyholm TKM, Engberg O, Hautala V, Tsuchikawa H, Lin K-L, Murata M, Slotte JP
Biophysical Journal
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A1 Journal article (refereed)
Lateral Segregation of Palmitoyl Ceramide-1-Phosphate in Simple and Complex Bilayers (2019)
Md. Abdullah Al Sazzad, Tomokazu Yasuda, Thomas K.M. Nyholm, J. Peter Slotte
Biophysical Journal
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A1 Journal article (refereed)
Lipid-Surrounding Water Molecules Probed by Time-Resolved Emission Spectra of Laurdan (2019)
Watanabe N, Suga K, Slotte JP, Nyholm TKM, Umakoshi H
Langmuir
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A1 Journal article (refereed)
Membrane Localization and Lipid Interactions of Common Lipid-Conjugated Fluorescence Probes (2019)
Engberg O, Scheidt HA, Nyholm TKM, Slotte JP, Huster D
Langmuir
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A1 Journal article (refereed)
Natural Ceramides and Lysophospholipids Cosegregate in Fluid Phosphatidylcholine Bilayers (2019)
Md. Abdullah Al Sazzad, Anna Möuts, Juan Palacios-Ortega, Kai-Lan Lin, Thomas K. M. Nyholm, J. PeterSlotte
Biophysical Journal
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A1 Journal article (refereed)
Nonlamellar-Phase-Promoting Colipids Enhance Segregation of Palmitoyl Ceramide in Fluid Bilayers (2019)
Möuts A, Yamamoto T, Nyholm TKM, Murata M, Slotte JP
Biophysical Journal
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A1 Journal article (refereed)
Solvatochromic Modeling of Laurdan for Multiple Polarity Analysis of Dihydrosphingomyelin Bilayer (2019)
Watanabe N, Goto Y, Suga K, Nyholm TKM, Slotte JP, Umakoshi H
Biophysical Journal
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A1 Journal article (refereed)
The Affinity of Sterols for Different Phospholipid Classes and Its Impact on Lateral Segregation (2019)
Nyholm TKM, Jaikishan S, Engberg O, Hautala V, Slotte JP
Biophysical Journal
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A1 Journal article (refereed)
A Ceramide-Regulated Element in the Late Endosomal Protein LAPTM4B Controls Amino Acid Transporter Interaction (2018)
Zhou KC, Dichlberger A, Martinez-Seara H, Nyholm TKM, Li SQ, Kim YA, Vattulainen I, Ikonen E, Blom T
ACS Central Science
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A1 Journal article (refereed)
Bilayer Interactions among Unsaturated Phospholipids, Sterols, and Ceramide (2017)
Slotte JP, Yasuda T, Engberg O, Al Sazzad MA, Hautala V, Nyholm TKM, Murata M
Biophysical Journal
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A1 Journal article (refereed)
Comparison of Unsaturated Phospholipids Effect on Phase Separation in Cholesterol Free and Cholesterol Containing Bilayers (2016)
Oskar Engberg, Victor Hautala, Anders Kullberg, Thomas K.M Nyholm, J. Peter Slotte
Biophysical Journal
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A1 Journal article (refereed)
Effect of Lung Surfactant Protein SP-C and SP-C-Promoted Membrane Fragmentation on Cholesterol Dynamics
(2016)
Roldan N, Nyholm TK, Slotte JP, Perez-Gil J, Garcia-Alvarez B
Biophysical Journal
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A1 Journal article (refereed)
Lipid Interactions and Organization in Complex Bilayer Membranes
(2016)
Engberg O, Yasuda T, Hautala V, Matsumori N, Nyholm TK, Murata M, Slotte JP
Biophysical Journal
A1 Journal article (refereed)
The Affinity of Cholesterol for Different Phospholipids Affects Lateral Segregation in Bilayers
(2016)
Engberg O, Hautala V, Yasuda T, Dehio H, Murata M, Slotte JP, Nyholm TK
Biophysical Journal
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A1 Journal article (refereed)
Formation of an ordered phase by ceramides and diacylglycerols in a fluid phosphatidylcholine bilayer--Correlation with structure and hydrogen bonding capacity (2015)
Ekman P, Maula T, Yamaguchi S, Yamamoto T, Nyholm TK, Katsumura S, Slotte JP
BBA - Biomembranes
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A1 Journal article (refereed)
Formation of Gel-like Nanodomains in Cholesterol-Containing Sphingomyelin or Phosphatidylcholine Binary Membrane As Examined by Fluorescence Lifetimes and 2H NMR Spectra (2015)
Tomokazu Yasuda, Nobuaki Matsumori, Hiroshi Tsuchikawa, Max Lönnfors, Thomas K.M. Nyholm, J.Peter Slotte, Michio Murata
Langmuir
A1 Journal article (refereed)
Lipid-protein interplay and lateral organization in biomembranes (2015)
Nyholm T.K.M.
Chemistry and Physics of Lipids
A1 Journal article (refereed)
Lateral sorting in model membranes by cholesterol-mediated hydrophobic matching. (2011)
Kaiser, Orłowski, Róg, Nyholm, Chai, Feizi, Lingwood, Vattulainen, Simons
Proceedings of the National Academy of Sciences
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A1 Journal article (refereed)
Membrane bilayer properties of sphingomyelins with amide-linked 2- or 3-hydroxylated fatty acids. (2011)
Ekholm, Jaikishan, Lönnfors, Nyholm, Slotte
BBA - Biochimica et Biophysica Acta
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A1 Journal article (refereed)
N- and O-methylation of sphingomyelin markedly affects its membrane properties and interactions with cholesterol. (2011)
Björkbom, Róg, Kankaanpää, Lindroos, Kaszuba, Kurita, Yamaguchi, Yamamoto, Jaikishan, Paavolainen, Päivärinne, Nyholm, Katsumura, Vattulainen, Slotte
BBA - Biochimica et Biophysica Acta
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A1 Journal article (refereed)
Probing the lipid-protein interface using model transmembrane peptides with a covalently linked acyl chain. (2011)
Nyholm, van Duyl, Rijkers, Liskamp, Killian
Biophysical Journal
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A1 Journal article (refereed)
Sterols have higher affinity for sphingomyelin than for phosphatidylcholine bilayers even at equal acyl-chain order. (2011)
Lönnfors, Doux, Killian, Nyholm, Slotte
Biophysical Journal
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A1 Journal article (refereed)
Effect of sphingomyelin headgroup size on molecular properties and interactions with cholesterol. (2010)
Björkbom, Róg, Kaszuba, Kurita, Yamaguchi, Lönnfors, Nyholm, Vattulainen, Katsumura, Slotte
Biophysical Journal
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A1 Journal article (refereed)
Sterol affinity for bilayer membranes is affected by their ceramide content and the ceramide chain length. (2010)
Nyholm, Grandell, Westerlund, Slotte
BBA - Biochimica et Biophysica Acta
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A1 Journal article (refereed)
Transmembrane peptides influence the affinity of sterols for phospholipid bilayers. (2010)
Nyström, Lönnfors, Nyholm
Biophysical Journal
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A1 Journal article (refereed)
N-palmitoyl-sulfatide participates in lateral domain formation in complex lipid bilayers (2008)
Björkqvist YJE, Nybond S, Nyholm TKM, Slotte JP, Ramstedt B
BBA - Biomembranes
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A1 Journal article (refereed)
Binding properties of HABA-type azo derivatives to avidin and avidin-related protein 4 (2006)
Susanna Repo, Tiina A.Paldanius, Vesa P. Hytönen, Thomas K. M. Nyholm, Katrin K. Halling, Juhani Huuskonen, Olli T. Pentikäinen, Kari Rissanen, J. Peter Slotte, Tomi T. Airenne, Tiina A. Salminen, Markku S .Kulomaa, Mark S.Johnson
Chemistry and Biology
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A2 Review article, Literature review, Systematic review
Peptides in lipid bilayers: the power of simple models. (2006)
Killian, Nyholm
Current Opinion in Structural Biology
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A1 Journal article (refereed)
Avidin related protein 2 shows unique structural and functional features among the avidin protein family (2005)
Vesa P Hytönen, Juha AE Määttä, Heidi Kidron, Katrin K Halling, Jarno Hörhä, Tuomas Kulomaa, Thomas KM Nyholm, Mark S Johnson, Tiina A Salminen, Markku S Kulomaa and Tomi T Airenne
BMC Biotechnology
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A1 Journal article (refereed)
Domain Formation and Stability in Complex Lipid Bilayers as Reported by Cholestatrienol (2005)
Y Jenny E Björkqvist, Thomas KM Nyholm, J Peter Slotte, Bodil Ramstedt
Biophysical Journal
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A1 Journal article (refereed)
Jararhagin-derived RKKH peptides induce structural changes in alpha I-1 domain of human integrin alpha(1)beta(1) (2004)
Nymalm Y, Puranen JS, Nyholm TKM, Käpylä J, Kidron H, Pentikäinen OT, Airenne TT, Heino J, Slotte JP, Johnson MS, Salminen TA
Journal of Biological Chemistry
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A1 Journal article (refereed)
Miscibility of acyl-chain defined phosphatidylcholines with N-palmitoyl sphingomyelin in bilayer membranes. (2004)
Térová, Slotte, Nyholm
BBA - Biochimica et Biophysica Acta
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Last updated on 2020-06-01 at 08:09