Oligosaccharides for pharmaceutical applications

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Publication Details

List of Authors: Jani Rahkila, Tiina Saloranta, Reko Leino
Editors: Dmitry Murzin, Olga Simakova
Place: Cambridge
Publication year: 2016
Publisher: Royal Society of Chemistry
Book title: Biomass sugars for non-fuel applications
Title of series: RSC Green Chemistry
Number in series: 44
Start page: 205
End page: 227
ISBN: 978-1-78262-113-3
eISBN: 978-1-78262-207-9
ISSN: 1757-7039


Carbohydrates, being the most abundant class of biopolymers on earth, have, due to their structural diversity and inherent chirality, been subject to comprehensive biological investigations. Their biological importance is unquestionable, as a wide range of biological recognition and communication phenomena depend on complex oligo- and polysaccharide structures. This also makes carbohydrates attractive targets for developing new pharmaceuticals. In this chapter, a fundamental overview of the synthesis of oligosaccharides from the viewpoint of both traditional synthetic methods as well as fully automated methodologies is provided. Furthermore, selected commercially available oligosaccharide pharmaceuticals as well as promising new compounds under development are briefly discussed.

Last updated on 2020-22-01 at 04:55