Perspectives of Printing Technologies in Continuous Drug Manufacturing

B2 Book section


Internal Authors/Editors


Publication Details

List of Authors: Sandler N, Ihalainen P
Editors: Peter Kleinebudde, Johannes Khinast, Jukka Rantanen
Publisher: John Wiley & Sons, Ltd
Publication year: 2017
Publisher: John Wiley & Sons
Book title: Continuous Manufacturing of Pharmaceuticals
Start page: 525
End page: 549
ISBN: 9781119001324
eISBN: 9781119001348
eISSN: 9781119001348


Abstract

This chapter discusses and gives future perspectives of the use of printing technologies in the manufacture of drugs. It describes the following techniques: inkjet printing (drop deposition); flexographic printing; and fused filament deposition. The promising advancements in printing technologies support dose personalization development in the pharmaceutical industry and can contribute to attractive options for continuous manufacturing. Reliable and robust methods for the quality control of created formulations are needed if printing becomes a viable option in point of care applications. Most application examples in the chapter deal with desktop flexography and research-scale inkjet models that are available for drug delivery system prototype fabrication for accurate dosing, multi-dosing, and material deposition in general. Due to the varying nature of inks and the complexity in the structures to be produced, single printing methods cannot meet all the needs required in fabricating complex multilayer and composite (multi-component) structures.


Keywords

3D printing, Continuous drug manufacturing, Drug delivery systems, Flexographic printing, Fused filament deposition, Inkjet printing, Pharmaceutical industry, Quality control

Last updated on 2019-14-12 at 02:45