Compression properties and dissolution of bioactive glass S53P4 and n-butyl-2 cyanoacrylate tissue adhesive-composite

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Jussi Sarin, Markus Hiltunen, Leena Hupa, Jaakko Pulkkinen, Pekka K. Vallittu
Publication year: 2016
Journal: Bio-Medical Materials and Engineering
Volume number: 27
Issue number: 4
Start page: 425
End page: 436
eISSN: 1878-3619


Abstract

Bioactive glass (BG)-containing fiber-reinforced composite implants, typically screw-retained, have started to be used clinically. In this study, we tested the mechanical strength of composites formed by a potential implant adhesive of n-butyl-2-cyanoacrylate glue and BG S53P4 particles. Water immersion for 3, 10 or 30 days had no adverse effect on the compression strength. When cyanoacrylate glue-BG-composites were subjected to simulated body fluid immersion, the average pH rose to 7.52 (SD 0.066) from the original value of 7.35 after 7 days, and this pH increment was smaller compared to BG particle-group or fibrin glue-BG-composite group. Based on these results n-butyl-2 cyanoacrylate glue, by potentially producing a strong adhesion, might be considered a possible alternative for fixation of BG S53P4 containing composite implants. However, the mechanical and solubility properties of the cyanoacrylate glue may not encourage the use of this tissue adhesive with BG particles.

Last updated on 2019-13-11 at 03:16