Nanodiamond based complexes for prolonged dexamethasone release

A4 Konferenspublikationer


Interna författare/redaktörer


Publikationens författare: Laptinskiy KA, Kettiger H, Shenderova OA, Burikov SA, Rosenholm JM, Dolenko TA
Redaktörer: Dmitry Engelevich Postnov
Förläggare: International Society for Optics and Photonics
Publiceringsår: 2019
Tidskrift: Proceedings of SPIE
Förläggare: Society of Photo-Optical Instrumentation Engineers (SPIE)
Moderpublikationens namn: Saratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions
Seriens namn: Proceedings of SPIE
Volym: 11067
ISBN: 9781510628243


Abstrakt

In the article for the first time the properties of nanodiamond
complexes with dexamethasone obtained by two different approaches -
attachment of the drug to the surface of nanodiamond and to the
nanodiamond, covered by silica layer – were compared. It was found that
the synthesized nanocomposite ND@silica@Dex is able to retain a greater
amount of drug and allows achieving prolonged release of dexamethasone.
These properties of the complexes ND@silica@Dex provide prospects for
their use as drug carries.


Nyckelord

nanodiamonds

Senast uppdaterad 2020-22-09 vid 05:06