Cytotoxic activity of some glycoconjugates including saponins and anthracyclines

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Filip S. Ekholm, Ágnes Berényi, Lucas Lagerquist, Tiina Saloranta, István Zupkó, Gyula Schneider, János Wölfling, Reko Leino
Publisher: Elsevier
Publication year: 2012
Journal: Carbohydrate Research
Journal acronym: CARBOHYD RES
Volume number: 356
Start page: 295
End page: 298
Number of pages: 4
ISSN: 0008-6215


Abstract

Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed. (C) 2012 Elsevier Ltd. All rights reserved.


Keywords

Cytotoxic activity, Saponins

Last updated on 2020-05-06 at 03:10