SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland.

A1 Journal article (refereed)

Internal Authors/Editors

Publication Details

List of Authors: Peuhu, Kaukonen, Lerche, Saari, Guzmán, Rantakari, De Franceschi, Wärri, Georgiadou, Jacquemet, Mattila, Virtakoivu, Liu, Attieh, Silva, Sundberg, Betz, Deugnier, Salmi, Ivaska, Eliceiri
Publication year: 2017
Journal: EMBO Journal
Journal acronym: EMBO J
Volume number: 36
Issue number: 2
Start page: 165
End page: 182
ISSN: 1460-2075


mammary gland stromal fibroblasts demonstrated defects in collagen fibre assembly, collagen contraction and degradation in vitro Together, these data imply that SHARPIN regulates the normal invasive mammary gland branching morphogenesis in an epithelial cell extrinsic manner by controlling the organisation of the stromal ECM.

Last updated on 2020-31-03 at 04:30