Reductive amination of ketones with benzylamine over gold supported on different oxides

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)

Interna författare/redaktörer

Publikationens författare: E. Kolobova, P. Mäki-Arvela, A. Pestryakov, E. Pakrieva, L. Pascual, A. Smeds, J. Rahkila, T. Sandberg, J. Peltonen, D. Yu. Murzin
Publiceringsår: 2019
Tidskrift: Catalysis Letters
Tidskriftsakronym: Catal. Lett.
Volym: 149
Nummer: 12
Artikelns första sida, sidnummer: 3432
Artikelns sista sida, sidnummer: 3446
eISSN: 1572-879X


Reductive amination of cyclohexanone with benzylamine was investigated at 100 °C under 30 bar hydrogen in toluene with five different gold catalysts prepared by deposition–precipitation method and supported on TiO2, La2O3/TiO2, CeO2/TiO2, La2O3 and CeO2. Size of metallic gold varied in the range of 2.6–3.6 nm. The best catalysts in reductive amination of cyclohexanone with benzylamine were 4 wt% Au/TiO2 and 4 wt% Au/CeO2/TiO2 giving 72% and 79% yield of the desired amine. The most acidic and basic catalysts were also unselective and exhibited low activity towards imine hydrogenation. The best catalyst 4 wt% Au/CeO2/TiO2 gave in reductive amination of propiophenone 56% selectivity to the corresponding amine at 20% conversion in 5 h.

Senast uppdaterad 2020-21-02 vid 05:04