Handheld colorimeter as quality control tool for inkjet printed flexible levothyroxine doses for pediatric use

A1 Journal article (refereed)

Internal Authors/Editors

Publication Details

List of Authors: Henrika Wickström, Anouk Broos, Johan O Nyman, Ewelina Kortesmäki, Patrik Eklund, Thomas de Beer, Maren Preis, Niklas Sandler
Editors: Smita Salunke, Catherine Tuleu
Publication year: 2018
Journal: International Journal of Pharmaceutics
Publisher: Elsevier
Book title: Formulating Better Medicines for Children – European Paediatric Formulation Initiative (EuPFI) 2016
Journal acronym: Int. J. Pharm.
Number in series: 2
Volume number: 536
Issue number: 2
Start page: 508
End page: 509
eISSN: 1873-3476


There is a need to formulate and develop age- and weight-appropriate oral dosage forms for pediatric use. The aim of this work was to manufacture flexible doses of levothyroxine (T4) on an edible bilayered substrate using inkjet technology. The use of a handheld colorimeter as a quality control tool, to differentiate between doses with different color intensities, was also studied. The need for orally dissolvable T4 formulations was addressed in the Best Pharmaceuticals for Children Act (BPCA) Priority List of Needs in Pediatric Therapeutics of the National Health Institution of the United States (BPCA, 2012).

Last updated on 2020-20-09 at 06:22