Intermediate filament dynamics

A2 Granskningsartikel, litteraturgranskning, systematisk granskning

Interna författare/redaktörer

Publikationens författare: Eriksson JE, Opal P, Goldman RD
Publiceringsår: 1992
Tidskrift: Current Opinion in Cell Biology
Tidskriftsakronym: Curr Opin Cell Biol
Volym: 4
Nummer: 1
Artikelns första sida, sidnummer: 99
Artikelns sista sida, sidnummer: 104
ISSN: 0955-0674


The view of intermediate filaments as static cytoskeletal elements is changing. Studies of exogenous intermediate filament proteins, either microinjected or expressed from transfected genes, have demonstrated that a continuous incorporation of subunits into the polymerized filaments is taking place. This incorporation appears to be required for maintaining normal cytoplasmic networks of intermediate filaments. At the post-translational level, phosphorylation is an important factor in regulating dynamic aspects of intermediate filament organization and structure.

Senast uppdaterad 2020-30-09 vid 04:13