In vitro behavior of yttrium silica sol-gel microspheres

A1 Journal article (refereed)

Internal Authors/Editors

Publication Details

List of Authors: Cacaina D, Viitala R, Jokinen M, Ylanen H, Hupa M, Simon S
Publication year: 2005
Journal: Key Engineering Materials
Journal acronym: KEY ENG MAT
Volume number: 284-286
Start page: 411
End page: 414
Number of pages: 4
ISSN: 1013-9826


Biodegradable silica microspheres containing neutron activable yttrium cations were investigated as a potential material for in situ radiotherapy of cancers. The sol-gel method used for preparing the microspheres allows obtaining at relative low temperatures materials of high purity and homogeneity, with controlled rate of biodegradability. The influence of yttrium on the biodegradability of the silica microspheres was studied in a simulated body fluid (SBF). The chemical durability of the microspheres was investigated under in vitro conditions and the concentration of yttrium released from the microspheres was determined.


bioactive glasses, release behaviour, SBF, sol gel, yttrium

Last updated on 2020-23-02 at 03:57