Factors affecting in vitro bioactivity of glasses

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Zhang D, Ylanen HO, Hupa M, Hupa L
Publiceringsår: 2009
Tidskrift: Key Engineering Materials
Tidskriftsakronym: KEY ENG MAT
Volym: 396-398
Nummer: Bioceramics 21
Artikelns första sida, sidnummer: 115
Artikelns sista sida, sidnummer: 118
Antal sidor: 4
ISSN: 1013-9826


Abstrakt

In this work we summarize the most important findings of the influence of glass composition, sample shape and fluid circulation on in vitro behavior of bioactive glasses in the system Na(2)O-K(2)O-MgO-CaO-B(2)O(3)-P(2)O(5)-SiO(2). The sample shapes included plates, particulates, powdered glasses, glass fibers and sintered cones with interconnected porosity. The in vitro bioactivity was measured as the changes observed in the immersion solution, SBF, and the formation of reaction layers on the samples at 4 to 168 h immersion. A lower surface area to volume ratio gave smaller changes on the ion concentrations and pH of the immersion solution but thicker reaction layers on the glass surfaces. In particulate systems with circulating fluid the pH gradients in SBF were lower but surface layers more even than in static systems. The influence of glass composition on reaction layer formation as suggested by glass plates correlated with the in vitro behavior of glass particulates larger than 250 mu m, porous cones and fibers when using similar SA/V ratio.


Nyckelord

bioactive glass, fluid circulation, in-vitro bioactivity, particle size, SBF

Senast uppdaterad 2019-12-11 vid 05:52