In vitro behavior of fiber bundles and particles of bioactive glasses

A1 Journal article (refereed)

Internal Authors/Editors

Publication Details

List of Authors: Zhang D, Arstila H, Vedel E, Ylanen H, Hupa L, Hupa M
Publication year: 2008
Journal: Key Engineering Materials
Journal acronym: KEY ENG MAT
Volume number: 361-363
Issue number: 1. Bioceramics
Start page: 225
End page: 228
Number of pages: 4
ISSN: 1013-9826


In vitro reactions of bundles of fibers with diameters 20-500 mu m and crushed glasses of fractions 500-800 mu m were compared with the reactions of plates of the same bioactive glasses. The samples were immersed in simulated body fluid (SBF) for 2-7 days. After immersion the changes on the surfaces of the samples were observed by SEM/EDXA. Fir Layer formation on the glass surface was found to vary with glass composition, sample shape and local condition of single particle/fiber. However, only some fibers or particles formed similar in vitro reaction layers as the plates. The product form did not change the in vitro bioactivity of particles or fibers exposed to the bulk immersion solution. When the glasses were used as fiber bundles or particle beds, the packing degree and the flow of body fluids within the system interfered with the reactivity. Also a clear correlation between in vivo layer formation in bone and in vitro of the glass plates could be found.


fiber bundles, in-vitro reaction, particle, SBF

Last updated on 2020-21-02 at 06:01