Influence of the network modifier content on the bioactivity of silicate glasses

A1 Journal article (refereed)

Internal Authors/Editors

Publication Details

List of Authors: Borrajo JP, Liste S, Serra J, Gonzalez P, Chiussi S, Leon B, Perez-Amor M, Ylanen HO, Hupa M
Publication year: 2004
Journal: Key Engineering Materials
Journal acronym: KEY ENG MAT
Volume number: 254-256
Issue number: Bioceramics 16
Start page: 23
End page: 26
Number of pages: 4
ISSN: 1013-9826


The influence of the substitution of calcium oxide for sodium oxide in the composition of silica-based glasses on the in vitro bioactivity is presented. Valuable information on the active Si-O groups present in the glasses is obtained by Fourier Transform Raman and Infrared spectroscopies. In vitro test analysis by Scanning Electron Microscopy and Energy Dispersive X-ray Analysis show a correlation between the network disruption induced by the modifier type and the bioactive process. It is demonstrated that glasses with high SiO2 content can be bioactive depending on the alkali/alkali-earth modifiers ratio included into the vitreous silica network.


bioactive glasses, bioactivity, FTIR, network modifiers, Raman

Last updated on 2020-24-02 at 03:49