Lipid transfer proteins: classification, nomenclature, structure, and function

A2 Review article, Literature review, Systematic review


Internal Authors/Editors


Publication Details

List of Authors: Salminen TA, Blomqvist K, Edqvist J
Publisher: SPRINGER
Publication year: 2016
Journal: Planta
Journal acronym: PLANTA
Volume number: 244
Issue number: 5
Start page: 971
End page: 997
Number of pages: 27
ISSN: 0032-0935
eISSN: 1432-2048


Abstract

The non-specific lipid transfer proteins (LTPs) constitute a large protein family found in all land plants. They are small proteins characterized by a tunnel-like hydrophobic cavity, which makes them suitable for binding and transporting various lipids. The LTPs are abundantly expressed in most tissues. In general, they are synthesized with an N-terminal signal peptide that localizes the protein to spaces exterior to the plasma membrane. The in vivo functions of LTPs are still disputed, although evidence has accumulated for a role in the synthesis of lipid barrier polymers, such as cuticular waxes, suberin, and sporopollenin. There are also reports suggesting that LTPs are involved in signaling during pathogen attacks. LTPs are considered as key proteins for the plant's survival and colonization of land. In this review, we aim to present an overview of the current status of LTP research and also to discuss potential future applications of these proteins. We update the knowledge on 3D structures and lipid binding and review the most recent data from functional investigations, such as from knockout or overexpressing experiments. We also propose and argument for a novel system for the classification and naming of the LTPs.


Keywords

Cutin, LTP, NsLTP, Pollen, Protein structure, Suberin

Last updated on 2019-20-09 at 05:34