Rapid, simple, and efficient deprotection of benzyl/benzylidene protected carbohydrates by utilization of flow chemistry

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Ekholm FS, Mandity IM, Fulop F, Leino R
Förläggare: PERGAMON-ELSEVIER SCIENCE LTD
Publiceringsår: 2011
Tidskrift: Tetrahedron Letters
Tidskriftsakronym: TETRAHEDRON LETT
Volym: 52
Nummer: 16
Artikelns första sida, sidnummer: 1839
Artikelns sista sida, sidnummer: 1841
Antal sidor: 3
ISSN: 0040-4039


Abstrakt

A rapid, simple, and efficient deprotection procedure for the deprotection of benzyl- and/or benzylidene protected carbohydrates is described utilizing a continuous flow hydrogenation reactor. The method tolerates both acid- and base sensitive functional groups. The high efficiency, simple work-up, and short reaction time should make this method appealing to researchers working in the fields of carbohydrate chemistry and total synthesis. (C) 2011 Elsevier Ltd. All rights reserved.


Nyckelord

Benzyl/benzylidene, Flow chemistry, Heterogenous catalysis, Protective groups

Senast uppdaterad 2020-10-04 vid 07:29

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