Effect of modifier structure in the enantioselective hydrogenation of 1-phenyl-1,2-propanedione

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Toukoniitty E, Maki-Arvela P, Sjoholm R, Leino R, Salmi T, Murzin DY
Publisher: SPRINGER
Publication year: 2002
Journal: Reaction Kinetics and Catalysis Letters
Journal acronym: REACT KINET CATAL L
Volume number: 75
Issue number: 1
Start page: 21
End page: 30
Number of pages: 10
ISSN: 0133-1736


Abstract

Three different modifiers, (-)-cinchonidine, 10,11-dihydrocinchonidine and (+)-cinchonine were investigated in the enantioselective hydrogenation of an unsymmetrical dione, 1-phenyl-1,2-propanedione, over a commercial Pt/Al(2)O(3) catalyst. The catalytic activity, as well as the regio- and enantioselectivity in the hydroxyketones and diols formed were compared.


Keywords

chiral modifier, dione, enantioselective hydrogenation

Last updated on 2019-22-07 at 04:49