Immobilization of chiral ligands on polymer fibers by electron beam induced grafting and applications in enantioselective catalysis

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Degni S, Wilen CE, Leino R
Förläggare: AMER CHEMICAL SOC
Publiceringsår: 2001
Tidskrift: Organic Letters
Tidskriftsakronym: ORG LETT
Volym: 3
Nummer: 16
Artikelns första sida, sidnummer: 2551
Artikelns sista sida, sidnummer: 2554
Antal sidor: 4
ISSN: 1523-7060


Abstrakt

Styrenic TADDOL and L-prolinol-derived monomers were immobilized on polyethylene fibers by electron beam induced preirradiation grafting using styrene as comonomer. The polymer-supported chiral ligands were utilized as catalysts in the asymmetric addition of diethylzinc to benzaldehyde. Fiber-bound titanium TADDOLate gave a quantitative conversion of benzaldehyde to 1-phenylpropan-1-ol in a 97:3 S/R enantiomeric ratio. The catalyst was successfully regenerated and employed in subsequent reactions with retention of high enantioselectivities.

Senast uppdaterad 2020-19-02 vid 03:32