Rhamnosylation of lignans by a Streptomyces strain

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


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Publikationens författare: Patrik Eklund, Toni Holmström, Lamis Al-Ubaydy, Rainer Sjöholm, Juha Hakala
Förläggare: PERGAMON-ELSEVIER SCIENCE LTD
Publiceringsår: 2006
Tidskrift: Tetrahedron Letters
Tidskriftsakronym: TETRAHEDRON LETT
Volym: 47
Nummer: 10
Artikelns första sida, sidnummer: 1645
Artikelns sista sida, sidnummer: 1648
Antal sidor: 4
ISSN: 0040-4039


Abstrakt

Screening of 400 Streptomyces strains for biotransformation of the natural lignan matairesinol led to the identification of Streptomyces sp. LS136, capable of producing a single metabolite in moderate yields. Isolation and purification by preparative HPLC, followed by structural analyses by LC-MS and NMR, established the structure as matairesinol-4-O-rhamnoside. This bacterial strain was also used for rhamnosylation of the abundant natural lignans, hydroxymatairesinol and secoisolariciresinol. (c) 2006 Elsevier Ltd. All rights reserved.

Senast uppdaterad 2020-27-01 vid 04:21