Low kidney uptake of GLP-1R-targeting, beta cell-specific PET tracer, F-18-labeled [Nle(14),Lys(40)]exendin-4 analog, shows promise for clinical imaging

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Kirsi Mikkola, Cheng-Bim Yim, Paula Lehtiniemi, Saila Kauhanen, Miikka Tarkia, Tuula Tolvanen, Pirjo Nuutila, Olof Solin
Publisher: SPRINGER HEIDELBERG
Publication year: 2016
Journal: EJNMMI Research
Journal acronym: EJNMMI RES
Volume number: 6
Number of pages: 11
ISSN: 2191-219X


Abstract

Conclusions: [F-18] exendin-4 showed promise as a tracer for clinical imaging of pancreatic beta cells, due to its high specific uptake in native beta cells and its concomitant low kidney radioactivity uptake.


Keywords

beta cell, Exendin, F-18, Pancreas, PET

Last updated on 2020-23-01 at 04:52