Cytotoxic activity of some glycoconjugates including saponins and anthracyclines

A1 Journal article (refereed)

Internal Authors/Editors

Publication Details

List of Authors: Filip S. Ekholm, Ågnes Berényi, Lucas Lagerquist, Tiina Saloranta, István Zupkó, Gyula Schneider, János Wölfling, Reko Leino
Publication year: 2012
Journal: Carbohydrate Research
Journal acronym: CARBOHYD RES
Volume number: 356
Start page: 295
End page: 298
Number of pages: 4
ISSN: 0008-6215


Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed. (C) 2012 Elsevier Ltd. All rights reserved.


Anthracyclines, Cytotoxic activity, Glycoconjugates, Saponins

Last updated on 2020-05-06 at 06:08