Stereo- and regioselective glycosylation of 4-deoxy-epsilon-rhodomycinone

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Filip S. Ekholm, Lucas Lagerquist, Reko Leino
Publisher: ELSEVIER SCI LTD
Publication year: 2011
Journal: Carbohydrate Research
Journal acronym: CARBOHYD RES
Volume number: 346
Issue number: 6
Start page: 858
End page: 862
Number of pages: 5
ISSN: 0008-6215


Abstract

A method for the glycosylation of anthracyclines featuring benzoylated imidate donors has been developed and utilized in the synthesis of glycosylated 4-deoxy-epsilon-rhodomycinone derivatives. Due to its high efficiency, regioselectivity, stereoselectivity, and operational simplicity, the method should prove valuable to researchers working with glycosylation of tetracyclic compounds. (C) 2011 Elsevier Ltd. All rights reserved.


Keywords

Anthracycline, Glycosylation, Regioselectivite synthesis, Rhodomycinone glycosides, Stereoselective synthesis

Last updated on 2020-02-04 at 04:37