An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Blom T, Bergelin N, Meinander A, Löf C, Slotte JP, Eriksson JE, Törnquist K
Publisher: BIOMED CENTRAL LTD
Publication year: 2010
Journal: BMC Cell Biology
Journal acronym: BMC CELL BIOL
Volume number: 11
Start page: 1
End page: 11
Number of pages: 11
ISSN: 1471-2121
eISSN: 1471-2121


Abstract

Conclusions: We propose a self-amplifying loop of autocrine S1P with capacity to enhance cell survival. The mechanism provides increased understanding of the multifaceted roles of S1P in regulating cell fate during normal development and carcinogenesis.

Last updated on 2019-21-09 at 03:45