In vitro behavior of yttrium silica sol-​gel microspheres

A4 Konferenspublikationer

Interna författare/redaktörer

Publikationens författare: Cacaina D, Viitala R, Jokinen M, Ylanen H, Hupa M, Simon S
Redaktörer: Li Panjian, Zhang Kai, Colwell Clifford W.
Förlagsort: Switzerland ; United Kingdom
Publiceringsår: 2004
Tidskrift: Key Engineering Materials
Förläggare: Trans Tech Publications
Moderpublikationens namn: Proceedings of the 17th International Symposium of Ceramics in Medicine, The Annual Meeting of the International Society for Ceramics in Medicine
Seriens namn: Bioceramics
Volym: 17
Artikelns första sida, sidnummer: 411
Artikelns sista sida, sidnummer: 414
ISBN: 0-87849-961-X


Biodegradable silica microspheres containing neutron activable yttrium cations were investigated as a potential material for in situ radiotherapy of cancers. The sol-gel method used for preparing the microspheres allows obtaining at relative low temperatures materials of high purity and homogeneity, with controlled rate of biodegradability. The influence of yttrium on the biodegradability of the silica microspheres was studied in a simulated body fluid (SBF). The chemical durability of the microspheres was investigated under in vitro conditions and the concentration of yttrium released from the microspheres was determined.

Senast uppdaterad 2020-02-04 vid 04:53