In vitro behavior of yttrium silica sol-​gel microspheres

A4 Conference proceedings

Internal Authors/Editors

Publication Details

List of Authors: Cacaina D, Viitala R, Jokinen M, Ylanen H, Hupa M, Simon S
Editors: Li Panjian, Zhang Kai, Colwell Clifford W.
Place: Switzerland ; United Kingdom
Publication year: 2004
Journal: Key Engineering Materials
Publisher: Trans Tech Publications
Book title: Proceedings of the 17th International Symposium of Ceramics in Medicine, The Annual Meeting of the International Society for Ceramics in Medicine
Title of series: Bioceramics
Volume number: 17
Start page: 411
End page: 414
ISBN: 0-87849-961-X


Biodegradable silica microspheres containing neutron activable yttrium cations were investigated as a potential material for in situ radiotherapy of cancers. The sol-gel method used for preparing the microspheres allows obtaining at relative low temperatures materials of high purity and homogeneity, with controlled rate of biodegradability. The influence of yttrium on the biodegradability of the silica microspheres was studied in a simulated body fluid (SBF). The chemical durability of the microspheres was investigated under in vitro conditions and the concentration of yttrium released from the microspheres was determined.

Last updated on 2020-21-01 at 02:40