Senior Lecturer in Biochemistry

Peter Mattjus

Akademilektor, Biokemi
E-post: peter.mattjus@abo.fi


Yrkesmässiga intressen

Mattjus lab
Lipid Transfer Protein Research group

Glycosphingolipids act as recognition sites on the cell surface, aid to maintain the stability of membranes and connect cells to form tissues. Much remains unknown about the basic aspects of glycosphinglipid synthesis and breakdown and in particular, their intracellular transport. Our research focuses on understanding glycosphingolipid transport inside the cell.


Nyckelord

Glycolipid, glycolipid transfer protein, Lipids, lipid transfer, lipid transfer protein structure


Referentgranskade publikationer

A3 Bokavsnitt, kapitel i forskningsböcker
Indirect Lipid Transfer Protein Activity Measurements Using Quantification of Glycosphingolipid Production. (2019)
Backman APE, Halin J, Kjellberg MA, Mattjus P.
Visa på utgivarens sida
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Glucosylceramide acyl chain length is sensed by the glycolipid transfer protein. (2018)
Backman, Halin, Nurmi, Möuts, Kjellberg, Mattjus
PLoS ONE
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Nach Is a Novel Subgroup at an Early Evolutionary Stage of the CNC-bZIP Subfamily Transcription Factors from the Marine Bacteria to Humans (2018)
Zhu Y-P, Wang M, Xiang Y, Qiu L, Hu S, Zhang Z, Mattjus P, Zhu X, Zhang Y
International Journal of Molecular Sciences
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
ProLIF - quantitative integrin protein-protein interactions and synergistic membrane effects on proteoliposomes. (2018)
De Franceschi, Miihkinen, Hamidi, Alanko, Mai, Picas, Guzmán, Lévy, Mattjus, Goult, Goud, Ivaska
Journal of Cell Science
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1) (2018)
Marthe-Susanna Wegner, Lisa Gruber, Peter Mattjus, Gerd Geisslinger, Sabine Grösch
BMC Cancer
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor. (2018)
Xiang, Halin, Fan, Hu, Wang, Qiu, Zhang, Mattjus, Zhang
Toxicology and Applied Pharmacology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
UDP‑glucose ceramide glucosyltransferase activates AKT, promoted
proliferation, and doxorubicin resistance in breast cancer cells
(2018)
Marthe‑Susanna Wegner, Nina Schömel, Lisa Gruber, Stephanie Beatrice Örtel, Matti Aleksi Kjellberg, Peter Mattjus, Jennifer Kurz, Sandra Trautmann, Bing Peng, Martin Wegner, Manuel Kaulich, Robert Ahrends, Gerd Geisslinger, Sabine Grösch
Cellular and Molecular Life Sciences
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells (2018)
Marthe-Susanna Wegner, Nina Schömel, Lisa Gruber, Stephanie Beatrice Örtel, Matti Aleksi Kjellberg, Peter Mattjus, Jennifer Kurz, Sandra Trautmann, Bing Peng, Martin Wegner, Manuel Kaulich, Robert Ahrends, Gerd Geisslinger, Sabine Grösch
Cellular and Molecular Life Sciences
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A3 Bokavsnitt, kapitel i forskningsböcker
Purification and Validation of Lipid Transfer Proteins (2017)
Matti A. Kjellberg, Anders P.E. Backman, Anna Möuts, Peter Mattjus
Humana Press
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Specificity of the mammalian glycolipid transfer proteins (2016)
Mattjus P
Chemistry and Physics of Lipids
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Metabolic Conversion of Ceramides in HeLa Cells - A Cholesteryl Phosphocholine Delivery Approach (2015)
Kjellberg MA, Lönnfors M, Slotte JP, Mattjus P
PLoS ONE
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Alternation in the Glycolipid Transfer Protein Expression Causes Changes in the Cellular Lipidome (2014)
Matti A. Kjellberg, Anders P. E. Backman, Henna Ohvo-Rekilä, Peter Mattjus
PLoS ONE
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Membranes and mammalian glycolipid transferring proteins (2014)
Jessica Tuuf, Peter Mattjus
Chemistry and Physics of Lipids
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Glycolipid Transfer Protein Expression Is Affected by Glycosphingolipid Synthesis (2013)
Kjellberg MA, Mattjus P
PLoS ONE
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi (2013)
D'Angelo G, Uemura T, Chuang CC, Polishchuk E, Santoro M, Ohvo-Rekilä H, Sato T, Di Tullio G, Varriale A, D'Auria S, Daniele T, Capuani F, Johannes L, Mattjus P, Monti M, Pucci P, Williams RL, Burke JE, Platt FM, Harada A, De Matteis MA
Nature
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Effects of bile salts on glucosylceramide containing membranes (2011)
Halin J, Mattjus P
BBA - Biomembranes
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Monitoring glycolipid transfer protein activity and membrane interaction with the surface plasmon resonance technique (2011)
Ohvo-Rekilä H, Mattjus P
BBA - Biomembranes
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
The intermembrane ceramide transport catalyzed by CERT is sensitive to the lipid environment (2011)
Tuuf J, Kjellberg MA, Molotkovsky JG, Hanada K, Mattjus P
BBA - Biomembranes
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Glycolipid transfer proteins and membrane interaction (2009)
Mattjus P
BBA - Biomembranes
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
The glycolipid transfer protein interacts with the vesicle-associated membrane protein-associated protein VAP-A (2009)
Tuuf J, Wistbacka L, Mattjus P
Biochemical and Biophysical Research Communications
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Identification of a glycosphingolipid transfer protein GLTP1 in Arabidopsis thaliana (2008)
West G, Viitanen L, Alm C, Mattjus P, Salminen TA, Edqvist J
FEBS Journal
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Glycolipid transfer proteins (2007)
Brown RE, Mattjus P
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide (2007)
D'Angelo G, Polishchuk E, Di Tullio G, Santoro M, Di Campli A, Godi A, West G, Bielawski J, Chuang CC, van der Spoel AC, Platt FM, Hannun YA, Polishchuk R, Mattjus P, De Matteis MA
Nature
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Human glycolipid transfer protein - intracellular localization and effects on the sphingolipid synthesis (2007)
Tuuf J, Mattjus P
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Membrane curvature effects on glycolipid transfer protein activity (2007)
Nylund M, Fortelius C, Palonen EK, Molotkovsky JG, Mattjus P
Langmuir
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis (2007)
Halter D, Neumann S, van Dijk SM, Wolthoorn J, De Maziere AM, Vieira OV, Mattjus P, Klumperman J, van Meer G, Sprong H
Journal of Cell Biology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Characterization of SCP-2 from Euphorbia lagascae reveals that a single Leu/Met exchange enhances sterol transfer activity (2006)
Viitanen L, Nylund M, Eklund DM, Alm C, Eriksson AK, Tuuf J, Salminen TA, Mattjus P, Edqvist J
FEBS Journal
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Galactose oxidase action on galactose containing glycolipids - a fluorescence method (2006)
Fortelius M, Mattjus P
Chemistry and Physics of Lipids
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Membrane interaction and activity of the glycolipid transfer protein (2006)
West G, Nylund M, Slotte JP, Mattjus P
BBA - Biomembranes
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Molecular features of phospholipids that affect glycolipid transfer protein-mediated galactosylceramide transfer between vesicles (2006)
Nylund M, Kjellberg MA, Molotkovsky JG, Byun HS, Bittman R, Mattjus P
BBA - Biomembranes
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Structural evidence for adaptive ligand binding of glycolipid transfer protein (2006)
Airenne TT, Kidron H, Nymalm Y, Nylund M, West G, Mattjus P, Salminen TA
Journal of Molecular Biology
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Protein mediated glycolipid transfer is inhibited FROM sphingomyelin membranes but enhanced TO sphingomyelin containing raft like membranes (2005)
Nylund M, Mattjus P
BBA - Biomembranes
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Synthesis, characterisation and theoretical calculations of 2,6-diaminopurine etheno derivatives (2005)
Virta P, Koch A, Roslund MU, Mattjus P, Kleinpeter E, Kronberg L, Sjoholm R, Klika KD
Organic and Biomolecular Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
The 3-hydroxy group and 4,5-trans double bond of sphingomyelin are essential for modulation of galactosylceramide transmembrane asymmetry (2005)
Malewicz B, Valiyaveettil JT, Jacob K, Byun HS, Mattjus P, Baumann WJ, Bittman R, Brown RE
Biophysical Journal
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Crystallization and X-ray analysis of bovine glycolipid transfer protein (2004)
West G, Nymalm Y, Airenne TT, Kidron H, Mattjus P, Salminen TT
Acta Crystallographica Section D: Biological Crystallography
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
New nucleoside analogs from 2-amino-9-(β-D-ribofuranosyl)purine (2004)
Virta P, Holmström T, Roslund MU, Mattjus P, Kronberg L, Sjöholm R
Organic and Biomolecular Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Plants express a lipid transfer protein with high similarity to mammalian sterol carrier protein-2 (2004)
Edqvist J, Rönnberg E, Rosenquist S, Blomqvist K, Viitanen L, Salminen TA, Nylund M, Tuuf J, Mattjus P
Journal of Biological Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Glycolipid intermembrane transfer is accelerated by HET-C2, a filamentous fungus gene product involved in the cell-cell incompatibility response (2003)
Mattjus P, Turcq B, Pike HM, Molotkovsky JG, Brown RE
Biochemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Probing for preferential interactions among sphingolipids in bilayer vesicles using the glycolipid transfer protein (2002)
Mattjus P, Kline A, Pike HM, Molotkovsky JG, Brown RE
Biochemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Sphingomyelin modulates the transbilayer distribution of galactosylceramide in phospholipid membranes (2002)
Mattjus P, Malewicz B, Valiyaveettil JT, Baumann WJ, Bittman R, Brown RE
Journal of Biological Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Involvement of the acid sphingomyelinase pathway in UVA-induced apoptosis (2001)
Zhang YG, Mattjus P, Schmid PC, Dong ZM, Zhong SP, Ma WY, Brown RE, Bode AM, Schmid HHO, Dong ZG
Journal of Biological Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Charged membrane surfaces impede the protein-mediated transfer of glycosphingolipids between phospholipid bilayers (2000)
Mattjus P, Pike HM, Molotkovsky JG, Brown RE
Biochemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Cloning and expression of glycolipid transfer protein from bovine and porcine brain (2000)
Lin X, Mattjus P, Pike HM, Windebank AJ, Brown RE
Journal of Biological Chemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Involvement of nuclear factor of activated T cells activation in UV response - Evidence from cell culture and transgenic mice (2000)
Huang CS, Mattjus P, Ma WY, Rincon M, Chen NY, Brown RE, Dong ZG
Journal of Biological Chemistry
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
A fluorescence resonance energy transfer approach for monitoring protein-mediated glycolipid transfer between vesicle membranes (1999)
Mattjus P, Molotkovsky JG, Smaby JM, Brown RE
Analytical Biochemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
The influence of hydrophobic mismatch on androsterol/phosphatidylcholine interactions in model membranes (1998)
Ohvo-Rekila H, Mattjus P, Slotte JP
BBA - Biomembranes
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Does cholesterol discriminate between sphingomyelin and phosphatidylcholine in mixed monolayers containing both phospholipids? (1996)
Mattjus P, Slotte JP
Chemistry and Physics of Lipids
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Molecular interaction and lateral domain formation in monolayers containing cholesterol and phosphatidylcholines with acyl- or alkyl-linked C16 chains (1996)
Mattjus P, Bittman R, Slotte JP
Langmuir
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
Lateral domain formation in cholesterol/phospholipid monolayers as affected by the sterol side chain conformation (1995)
Mattjus P, Bittman R, Vilcheze C, Slotte JP
BBA - Biomembranes
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
VISUALIZATION OF LATERAL PHASES IN CHOLESTEROL AND PHOSPHATIDYLCHOLINE MONOLAYERS AT THE AIR/WATER INTERFACE - A COMPARATIVE STUDY WITH 2 DIFFERENT REPORTER MOLECULES (1995)
SLOTTE JP, MATTJUS P
BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
AVAILABILITY FOR ENZYME-CATALYZED OXIDATION OF CHOLESTEROL IN MIXED MONOLAYERS CONTAINING BOTH PHOSPHATIDYLCHOLINE AND SPHINGOMYELIN (1994)
MATTJUS P, SLOTTE JP
Chemistry and Physics of Lipids
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A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
CHOLESTEROL TRANSPORT FROM PLASMA MEMBRANES TO INTRACELLULAR MEMBRANES IS INHIBITED BY 3-BETA-[2-(DIETHYLAMINO)ETHOXY]ANDROST-5-EN-17-ONE (1994)
HÄRMÄLÄ AS, PÖRN MI, MATTJUS P, SLOTTE JP
BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
INTERACTION OF CHOLESTEROL WITH SPHINGOMYELIN IN MONOLAYERS AND VESICLES (1994)
BITTMAN R, KASIREDDY CR, MATTJUS P, SLOTTE JP
Biochemistry
A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)
MONOLAYER INTERACTION OF CHOLESTEROL WITH PHOSPHATIDYLCHOLINES - EFFECTS OF PHOSPHOLIPID ACYL CHAIN LENGTH (1994)
MATTJUS P, HEDSTRÖM G, SLOTTE JP
Chemistry and Physics of Lipids

Senast uppdaterad 2019-29-11 vid 14:07

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