Professor John Eriksson Professor, Cell Biology Email: john.eriksson@abo.fi Mobile: +358-504096624 Phone: +358-2-2153313

Peer-reviewed publications

A1 Journal article (refereed) A low-cost paper-based platform for fast and reliable screening of cellular interactions with materials (2020) Emil Rosqvist, Erik Niemelä, Johan Frisk, Heidi Öblom, Rajesh Koppolu, Hend Abdelkader, Diosangeles Soto Veliz, Marco Mennillo, Arun P. Venu, Petri Ihalainen, Melanie Aubert, Niklas Sandler, Carl-Eric Wilén, Martti Toivakka, John E Eriksson, Ronald Österbacka, Jouko Peltonen Journal of Materials Chemistry. B View on publisher's site

A1 Journal article (refereed) Nanoparticles carrying fingolimod and methotrexate enables targeted induction of apoptosis and immobilization of invasive thyroid cancer (2020) Niemelä E, Desai D, Niemi R, Doroszko M, Özliseli E, Kemppainen K, Rahman N, Sahlgren C, Törnquist K, Eriksson J European Journal of Pharmaceutics and Biopharmaceutics View on publisher's site

A1 Journal article (refereed) Human dermal fibroblast proliferation controlled by surface roughness of two-component nanostructured latex polymer coatings (2019) Emil Rosqvist, Erik Niemelä, Arun P. Venu, Ruut Kummala, Petri Ihalainen, Martti Toivakka, John E. Eriksson, Jouko Peltonen Colloids and Surfaces B: Biointerfaces View on publisher's site

A1 Journal article (refereed) Quantitative bioimage analytics enables measurement of targeted cellular stress response induced by celastrol-loaded nanoparticles (2019) Niemelä E, Desai D, Lundsten E, Rosenholm JM, Kankaanpää P, Eriksson JE Cell Stress and Chaperones View on publisher's site

A1 Journal article (refereed) Synthesis and Evaluation of Anisomelic acid-like Compounds for the Treatment of HPV-Mediated Carcinomas (2019) Senthilkumar R, Brusentsev Y, Paul P, Marimuthu P, Cheng F, Eklund PC, Eriksson JE Scientific Reports View on publisher's site

A1 Journal article (refereed) Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress. (2019) van Engeland N.C.A., Suarez Rodriguez F., Rivero-Müller A., Ristori T., Duran C.L., Stassen O.M.J.A., Antfolk D., Driessen R., Ruohonen S., Ruohonen S.T., Nuutinen S., Savontaus E., Loerakker S., Bayless K., Sjöqvist M., Bouten C.V.C., Eriksson J.E., Sahlgren C.M. Scientific Reports View on publisher's site

A1 Journal article (refereed) Photo-thermal and cytotoxic properties of inkjet-printed copper sulfide films on biocompatible latex coated substrates (2018) Jawad Sarfraz, Mykola Borzenkov, Erik Niemelä, Christian Weinberger, Björn Törngren, Emil Rosqvist, Maddalena Collini, Piersandro Pallavicini, John E. Eriksson, Jouko Peltonen, Petri Ihalainen, Giuseppe Chirico, Applied Surface Science View on publisher's site

A1 Journal article (refereed) Quantitative proteomic characterization and comparison of T helper 17 and induced regulatory T cells (2018) Imran Mohammad, Kari Nousiainen, Santosh D. Bhosale, Inna Starskaia, Robert Moulder, Anne Rokka, Fang Cheng, Ponnuswamy Mohanasundaram, John E. Eriksson, David R. Goodlett, Harri Lähdesmäki, Zhi Chen PLoS Biology View on publisher's site

A1 Journal article (refereed) Intermediate Filaments and the Regulation of Cell Motility during Regeneration and Wound Healing (2017) Cheng F, Eriksson JE Cold Spring Harbor Perspectives in Biology View on publisher's site

A1 Journal article (refereed) Internal epithelia in Drosophila display rudimentary competence to form cytoplasmic networks of transgenic human vimentin (2017) Josef Gullmets, Elin Torvaldson, Julia Lindqvist, Susumu Y. Imanishi, Pekka Taimen, Annika Meinander, and John E. Eriksson FASEB Journal View on publisher's site

A1 Journal article (refereed) Nestin contributes to skeletal muscle homeostasis and regeneration (2017) Julia Lindqvist, Elin Torvaldson, Josef Gullmets, Henok Karvonen, Andras Nagy, Pekka Taimen, John E. Eriksson Journal of Cell Science View on publisher's site

A1 Journal article (refereed) Selective regulation of Notch ligands during angiogenesis is mediated by vimentin (2017) Daniel Antfolk, Marika Sjöqvist, Fang Cheng, Kimmo Isoniemi, Camille L. Duran, Adolfo Rivero-Muller, Christian Antila , Rasmus Niemi , Sebastian Landor, Carlijn V.C. Bouten, Kayla J. Bayless, John E. Eriksson, Cecilia Maria Sahlgren Proceedings of the National Academy of Sciences View on publisher's site

A2 Review article, Literature review, Systematic review Tailored approaches in drug development and diagnostics: from molecular design to biological model systems (2017) Cecilia Sahlgren, Annika Meinander, Hongbo Zhang, Fang Cheng, Maren Preis, Chunlin Xu, Tiina A. Salminen, Diana Toivola, Daniel Abankwa, Ari Rosling, Didem Şen Karaman, Outi M. H. Salo-Ahen, Ronald Österbacka, John E. Eriksson, Stefan Willför, Ion Petre, Jouko Peltonen, Reko Leino, Mark Johnson, Jessica Rosenholm, Niklas Sandler Advanced Healthcare Materials View on publisher's site

A1 Journal article (refereed) Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA (2017) Jiu Y, Peranen J, Schaible N, Cheng F, Eriksson JE, Krishnan R, Lappalainen P Journal of Cell Science View on publisher's site

A1 Journal article (refereed) Deleterious assembly of the lamin A/C mutant p.S143P causes ER stress in familial dilated cardiomyopathy (2016) West G, Gullmets J, Virtanen L, Li SP, Keinanen A, Shimi T, Mauermann M, Helio T, Kaartinen M, Ollila L, Kuusisto J, Eriksson JE, Goldman RD, Herrmann H, Taimen P Journal of Cell Science View on publisher's site

A1 Journal article (refereed) Development of nanocellulose scaffolds with tunable structures to support 3D cell culture (2016) Jun Liu, Fang Cheng, Henrik Grénman, Steven Spoljaric, Jukka Seppälä, John E. Eriksson, Stefan Willför, Chunlin Xu Carbohydrate Polymers View on publisher's site

A1 Journal article (refereed) Granzyme B deficiency protects against angiotensin II–induced cardiac fibrosis (2016) Yue Shen, Fang Cheng, Mehul Sharma, Yulia Merkulova, Sheetal A. Raithatha, Leigh G. Parkinson, Hongyan Zhao, Kathryn Westendorf, Lubos Bohunek, Tatjana Bozin, Ivy Hsu, Lisa S. Ang, Sarah J. Williams, R. Chris Bleackley, John E. Eriksson, Michael A. Seidman, Bruce M. McManus, David J. Granville American Journal of Pathology View on publisher's site

A1 Journal article (refereed) Plasma Protein Binding of Anisomelic Acid: Spectroscopy and Molecular Dynamic Simulations (2016) Rajendran Senthilkumar, Parthiban Marimuthu, Preethy Paul, Yesaiyan Manojkumar, Sankaralingam Arunachalam, John E Eriksson, Mark S. Johnson Journal of Chemical Information and Modeling View on publisher's site

A1 Journal article (refereed) PP2A Inhibitor PME-1 Drives Kinase Inhibitor Resistance in Glioma Cells (2016) Kaur A, Denisova OV, Qiao X, Jumppanen M, Peuhu E, Ahmed SU, Raheem O, Haapasalo H, Eriksson J, Chalmers AJ, Laakkonen P, Westermarck J Cancer Research View on publisher's site

A1 Journal article (refereed) Studying Nestin and its Interrelationship with Cdk5 (2016) Julia Lindqvist, Num Wistbacka, John E. Eriksson Methods in Enzymology Elsevier

A1 Journal article (refereed) Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β–Slug signaling (2016) Fang Cheng, Yue Shen, Ponnuswamy Mohanasundaram, Michelle Lindström, Johanna Ivaska, Tor Ny, John E. Eriksson Proceedings of the National Academy of Sciences View on publisher's site

A1 Journal article (refereed) Bidirectional Interplay between Vimentin Intermediate Filaments and Contractile Actin Stress Fibers (2015) Jiu YM, Lehtimaki J, Tojkander S, Cheng F, Jaalinoja H, Liu XN, Varjosalo M, Eriksson JE, Lappalainen P Cell Reports View on publisher's site

A1 Journal article (refereed) Cyclin-dependent kinase 5 acts as a critical determinant of AKT-dependent proliferation and regulates differential gene expression by the androgen receptor in prostate cancer cells (2015) Lindqvist J, Imanishi SY, Torvaldson E, Malinen M, Remes M, Örn F, Palvimo JJ, Eriksson JE Molecular Biology of the Cell View on publisher's site

A1 Journal article (refereed) Keratins Stabilize Hemidesmosomes through Regulation of beta 4-Integrin Turnover (2015) Seltmann K, Cheng F, Wiche G, Eriksson JE, Magin TM Journal of Investigative Dermatology View on publisher's site

A2 Review article, Literature review, Systematic review Phosphorylation of lamins determine their structural properties and signaling functions (2015) Elin Torvaldson, Vitaly Kochin, John E. Eriksson Nucleus View on publisher's site

A1 Journal article (refereed) Sphingolipids inhibit vimentin-dependent cell migration (2015) Hyder C, Kemppainen K, Isoniemi K, Imanishi SY, Goto H, Inagaki M, Fazeli E, Eriksson JE, Törnquist K Journal of Cell Science

A1 Journal article (refereed) Sugar-decorated mesoporous silica nanoparticles as delivery vehicles for the poorly soluble drug celastrol enables targeted induction of apoptosis in cancer cells (2015) Niemelä E, Desai D, Nkizinkiko Y, Eriksson JE, Rosenholm JM European Journal of Pharmaceutics and Biopharmaceutics View on publisher's site

A1 Journal article (refereed) Targeted delivery of a novel anticancer compound anisomelic acid using chitosan-coated porous silica nanorods for enhancing the apoptotic effect (2015) Senthilkumar R, Şen Karaman D, Paul P, Björk EM, Odén M, Eriksson JE, Rosenholm JM Biomaterials Science View on publisher's site

A1 Journal article (refereed) Vimentin-ERK Signaling Uncouples Slug Gene Regulatory Function (2015) Virtakoivu R, Mai A, Mattila E, De Franceschi N, Imanishi SY, Corthals G, Kaukonen R, Saari M, Cheng F, Torvaldson E, Kosma VM, Mannermaa A, Muharram G, Gilles C, Eriksson J, Soini Y, Lorens JB, Ivaska J Cancer Research View on publisher's site

A3 Book section, Chapters in research books Intermediate Filaments (2014) Fang Cheng, John E Eriksson John Wiley & Sons View on publisher's site

A1 Journal article (refereed) Interphase phosphorylation of lamin A (2014) Kochin V, Shimi T, Torvaldson E, Adam SA, Goldman A, Pack CG, Melo-Cardenas J, Imanishi SY, Goldman RD, Eriksson JE Journal of Cell Science View on publisher's site

A1 Journal article (refereed) Nestin regulates prostate cancer cell invasion by influencing the localisation and functions of FAK and integrins (2014) Hyder CL, Lazaro G, Pylvänäinen JW, Roberts MW, Qvarnström SM, Eriksson JE. Journal of Cell Science View on publisher's site

A1 Journal article (refereed) Novel action modality of the diterpenoid anisomelic acid causes depletion of E6 and E7 viral oncoproteins in HPV-transformed cervical carcinoma cells (2014) Paul, Rajendran, Peuhu, Alshatwi, Akbarsha, Hietanen, Eriksson Biochemical Pharmacology View on publisher's site

A1 Journal article (refereed) PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner (2014) Sjöqvist M, Antfolk D, Ferraris S, Rraklli V, Haga C, Antila C, Mutvei A, Imanishi SY, Holmberg J, Jin S, Eriksson JE, Lendahl U, Sahlgren C Cell Research View on publisher's site

A1 Journal article (refereed) Regulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cells (2014) de Thonel A, Hazoumé A, Kochin V, Isoniemi K, Jego G, Fourmaux E, Hammann A, Mjahed H, Filhol O, Micheau O, Rocchi P, Mezger V, Eriksson JE, Rangnekar VM, Garrido C Cell Death and Disease View on publisher's site

A1 Journal article (refereed) The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival (2014) Koenig A, Buskiewicz IA, Fortner KA, Russell JQ, Asaoka T, He YW, Hakem R, Eriksson JE, Budd RC Journal of Biological Chemistry View on publisher's site

A1 Journal article (refereed) The antitumor lignan Nortrachelogenin sensitizes prostate cancer cells to TRAIL-induced cell death by inhibition of the Akt pathway and growth factor signaling. (2013) Peuhu, Paul, Remes, Holmbom, Eklund, Sjöholm, Eriksson Biochemical Pharmacology View on publisher's site

A1 Journal article (refereed) Nucleolar AATF regulates c-Jun-mediated apoptosis (2012) Ferraris, Isoniemi, Torvaldson, Anckar, Westermarck, Eriksson Molecular Biology of the Cell View on publisher's site

A1 Journal article (refereed) Shape engineering vs organic modification of inorganic nanoparticles as a tool for enhancing cellular internalization (2012) Karaman, Desai, Senthilkumar, Johansson, Råtts, Odén, Eriksson, Sahlgren, Toivola, Rosenholm Nanoscale Research Letters View on publisher's site

A1 Journal article (refereed) A simple mass-action model for the eukaryotic heat shock response and its mathematical validation (2011) Petre I, Mizera A, Hyder CL, Meinander A, Mikhailov A, Morimoto RI, Sistonen L, Eriksson JE, Back RJ Natural Computing View on publisher's site

A1 Journal article (refereed) Insights into intermediate filament regulation from development to ageing (2011) Hyder, Isoniemi, Torvaldson, Eriksson Journal of Cell Science View on publisher's site

A4 Conference proceedings Mathematical modeling of apoptosis as a function of c-flip turnover and at random parameter distributions (2011) Toivonen HT, Saxen H, Westerlund M, Pettersson F, Meinander A, Eriksson JE Springer View on publisher's site

A1 Journal article (refereed) Modeling reveals that dynamic regulation of c-FLIP levels determines cell-to-cell distribution of CD95-mediated apoptosis (2011) Toivonen HT, Meinander A, Asaoka T, Westerlund M, Pettersson F, Mikhailov A, Eriksson JE, Saxén H Journal of Biological Chemistry View on publisher's site

A1 Journal article (refereed) Nestin as a regulator of Cdk5 in differentiating myoblasts (2011) Pallari, Lindqvist, Torvaldson, Ferraris, He, Sahlgren, Eriksson Molecular Biology of the Cell View on publisher's site

A1 Journal article (refereed) Nestin is not essential for development of the CNS but required for dispersion of acetylcholine receptor clusters at the area of neuromuscular junctions (2011) Mohseni, Sung, Murphy, Laliberte, Pallari, Henkelman, Georgiou, Xie, Quaggin, Thorner, Eriksson, Nagy Journal of Neuroscience View on publisher's site

A1 Journal article (refereed) Nestin negatively regulates postsynaptic differentiation of the neuromuscular synapse (2011) Yang, Dominguez, de Winter, Gould, Eriksson, Lee Nature Neuroscience View on publisher's site

A1 Journal article (refereed) Regulation of cell death by c-FLIP phosphorylation (2011) Asaoka, Kaunisto, Eriksson Advances in Experimental Medicine and Biology View on publisher's site

A1 Journal article (refereed) Workshop summary: cell death mechanisms controlled by the TNF family (2011) Eriksson JE, Vandenabeele P Advances in Experimental Medicine and Biology View on publisher's site

A1 Journal article (refereed) An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival (2010) Blom T, Bergelin N, Meinander A, Löf C, Slotte JP, Eriksson JE, Törnquist K BMC Cell Biology View on publisher's site

A1 Journal article (refereed) Cancer-cell-specific induction of apoptosis using mesoporous silica nanoparticles as drug-delivery vectors (2010) Rosenholm, Peuhu, Bate-Eya, Eriksson, Sahlgren, Lindén Small View on publisher's site

A1 Journal article (refereed) Inhibition of Akt signaling by the lignan matairesinol sensitizes prostate cancer cells to TRAIL-induced apoptosis (2010) Peuhu, Rivero-Müller, Stykki, Torvaldson, Holmbom, Eklund, Unkila, Sjöholm, Eriksson Oncogene View on publisher's site

A1 Journal article (refereed) In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification (2010) Blomster, Imanishi, Siimes, Kastu, Morrice, Eriksson, Sistonen Journal of Biological Chemistry View on publisher's site

A1 Journal article (refereed) Molecular targets for the protodynamic action of cis-urocanic acid in human bladder carcinoma cells (2010) Peuhu, Kaunisto, Laihia, Leino, Eriksson BMC Cancer View on publisher's site

A1 Journal article (refereed) Protein kinase Czeta regulates Cdk5/p25 signaling during myogenesis (2010) de Thonel, Ferraris, Pallari, Imanishi, Kochin, Hosokawa, Hisanaga, Sahlgren, Eriksson Molecular Biology of the Cell View on publisher's site

A1 Journal article (refereed) Vimentin is a functional partner of hormone sensitive lipase and facilitates lipolysis (2010) Shen, Patel, Eriksson, Kraemer Journal of Proteome Research View on publisher's site

A3 Book section, Chapters in research books A New Mathematical Model for the Heat Shock Response (2009) Petre I, Mizera A, Hyder CL, Mikhailov A, Eriksson JE, Sistonen L, Back RJ Springer View on publisher's site

A2 Review article, Literature review, Systematic review Introducing intermediate filaments: from discovery to disease (2009) Eriksson, Dechat, Grin, Helfand, Mendez, Pallari, Goldman Journal of Clinical Investigation View on publisher's site

A1 Journal article (refereed) Phosphopeptide enrichment with stable spatial coordination on a titanium dioxide coated glass slide (2009) Imanishi, Kouvonen, Smått, Heikkilä, Peuhu, Mikhailov, Ritala, Lindén, Corthals, Eriksson Rapid Communications in Mass Spectrometry View on publisher's site

A1 Journal article (refereed) PKC-mediated phosphorylation regulates c-FLIP ubiquitylation and stability (2009) Kaunisto, Kochin, Asaoka, Mikhailov, Poukkula, Meinander, Eriksson Cell Death and Differentiation View on publisher's site

A1 Journal article (refereed) Targeted intracellular delivery of hydrophobic agents using mesoporous hybrid silica nanoparticles as carrier systems (2009) Rosenholm, Peuhu, Eriksson, Sahlgren, Lindén Nano Letters View on publisher's site

A1 Journal article (refereed) Targeting of porous hybrid silica nanoparticles to cancer cells (2009) Rosenholm, Meinander, Peuhu, Niemi, Eriksson, Sahlgren, Lindén ACS Nano View on publisher's site

A1 Journal article (refereed) CD73 participates in cellular multiresistance program and protects against TRAIL-induced apoptosis (2008) Mikhailov, Sokolovskaya, Yegutkin, Amdahl, West, Yagita, Lahesmaa, Thompson, Jalkanen, Blokhin, Eriksson Journal of Immunology

A1 Journal article (refereed) Opposing roles for caspase and calpain death proteases in L-glutamate-induced oxidative neurotoxicity (2008) Elphick, Hawat, Toms, Meinander, Mikhailov, Eriksson, Kass Toxicology and Applied Pharmacology View on publisher's site

A2 Review article, Literature review, Systematic review Providing cellular signposts--post-translational modifications of intermediate filaments (2008) Hyder, Pallari, Kochin, Eriksson FEBS Letters View on publisher's site

A1 Journal article (refereed) Fever-like hyperthermia controls T Lymphocyte persistence by inducing degradation of cellular FLIPshort (2007) Meinander, Söderström, Kaunisto, Poukkula, Sistonen, Eriksson Journal of Immunology View on publisher's site

A2 Review article, Literature review, Systematic review Novel functions of vimentin in cell adhesion, migration, and signaling (2007) Ivaska, Pallari, Nevo, Eriksson Experimental Cell Research View on publisher's site

A1 Journal article (refereed) Optimization of phosphopeptide elution conditions in immobilized Fe(III) affinity chromatography (2007) Imanishi, Kochin, Eriksson Proteomics View on publisher's site

A1 Journal article (refereed) Reference-facilitated phosphoproteomics: fast and reliable phosphopeptide validation by microLC-ESI-Q-TOF MS/MS (2007) Imanishi, Kochin, Ferraris, de Thonel, Pallari, Corthals, Eriksson Molecular and Cellular Proteomics View on publisher's site

A1 Journal article (refereed) A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death (2006) Sahlgren, Pallari, He, Chou, Goldman, Eriksson EMBO Journal View on publisher's site

A1 Journal article (refereed) Fas costimulation of naive CD4 T cells is controlled by NF-κB signaling and caspase activity (2006) Maksimow M, Söderström TS, Jalkanen S, Eriksson JE, Hänninen A Journal of Leukocyte Biology View on publisher's site

A1 Journal article (refereed) Fast track to a phosphoprotein sketch - MALDI-TOF characterization of TLC-based tryptic phosphopeptide maps at femtomolar detection sensitivity (2006) Kochin V, Imanishi SY, Eriksson JE Proteomics View on publisher's site

A2 Review article, Literature review, Systematic review Intermediate filaments as signaling platforms (2006) Pallari, Eriksson Science's STKE : signal transduction knowledge environment View on publisher's site

A1 Journal article (refereed) Live cell detection of caspase-3 activation by a Discosoma-red-fluorescent-protein-based fluorescence resonance energy transfer construct (2006) Elphick, Meinander, Mikhailov, Richard, Toms, Eriksson, Kass Analytical Biochemistry View on publisher's site

A1 Journal article (refereed) Vimentin function in lymphocyte adhesion and transcellular migration (2006) Nieminen, Henttinen, Merinen, Marttila-Ichihara, Eriksson, Jalkanen Nature Cell Biology View on publisher's site

A1 Journal article (refereed) Binding and phosphorylation of par-4 by akt is essential for cancer cell survival (2005) Goswami, Burikhanov, de Thonel, Fujita, Goswami, Zhao, Eriksson, Tsuruo, Rangnekar Molecular Cell View on publisher's site

A1 Journal article (refereed) CD95 capping is ROCK-dependent and dispensable for apoptosis (2005) Söderström, Nyberg, Eriksson Journal of Cell Science View on publisher's site

A1 Journal article (refereed) Rapid turnover of c-FLIPshort is determined by its unique C-terminal tail (2005) Poukkula, Kaunisto, Hietakangas, Denessiouk, Katajamäki, Johnson, Sistonen, Eriksson Journal of Biological Chemistry View on publisher's site

A2 Review article, Literature review, Systematic review Regulation of death receptors--relevance in cancer therapies (2005) de Thonel, Eriksson Toxicology and Applied Pharmacology View on publisher's site

A1 Journal article (refereed) Approaches to study posttranslational regulation of intermediate filament proteins (2004) Kochin, Pallari, Pant, Eriksson Methods in Cell Biology

A2 Review article, Literature review, Systematic review Instant decisions: transcription-independent control of death-receptor-mediated apoptosis (2004) Tran, Meinander, Eriksson Trends in Biochemical Sciences View on publisher's site

A1 Journal article (refereed) Specific in vivo phosphorylation sites determine the assembly dynamics of vimentin intermediate filaments (2004) Eriksson, He, Trejo-Skalli, Härmälä-Braskén, Hellman, Chou, Goldman Journal of Cell Science View on publisher's site

A1 Journal article (refereed) Cdk5 regulates the organization of Nestin and its association with p35. (2003) Sahlgren CM, Mikhailov A, Vaittinen S, Pallari HM, Kalimo H, Pant HC, Eriksson JE Molecular and Cellular Biology View on publisher's site

A1 Journal article (refereed) Erythroid differentiation sensitizes K562 leukemia cells to TRAIL-induced apoptosis by downregulation of c-FLIP (2003) Hietakangas V, Poukkula M, Heiskanen KM, Karvinen JT, Sistonen L, Eriksson JE Molecular and Cellular Biology View on publisher's site

A1 Journal article (refereed) Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis (2003) Tran SEF, Meinander A, Holmström TH, Rivero-Muller A, Heiskanen KM, Linnau EK, Courtney MJ, Mosser DD, Sistonen L, Eriksson JE Cell Death and Differentiation View on publisher's site

A1 Journal article (refereed) Type-2A protein phosphatase activity is required to maintain death receptor responsiveness (2003) Härmälä-Brasken AS, Mikhailov A, Söderström TS, Meinander A, Holmström TH, Damuni Z, Eriksson JE Oncogene View on publisher's site

A1 Journal article (refereed) Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta (2002) Ivaska J, Nissinen L, Immonen N, Eriksson JE, Kähäri VM, Heino J Molecular and Cellular Biology

A1 Journal article (refereed) Multisite phosphorylation provides sophisticated regulation of transcription factors (2002) Holmberg CI, Tran SEF, Eriksson JE, Sistonen L Trends in Biochemical Sciences

A1 Journal article (refereed) Activation of the MKK4-JNK pathway during erythroid differentiation of K562 cells is inhibited by the heat shock factor 2-beta isoform (2001) Hietakangas, Elo, Rosenström, Coffey, Kyriakis, Eriksson, Sistonen FEBS Letters View on publisher's site

A1 Journal article (refereed) A time-resolved fluoroimmunometric assay for the detection of microcystins, cyanobacterial peptide hepatotoxins (2001) Mehto, Ankelo, Hinkkanen, Mikhailov, Eriksson, Spoof, Meriluoto Toxicon

A1 Journal article (refereed) Disturbances in hepatic cell-cycle regulation in mice with assembly-deficient keratins 8/18 (2001) Toivola DM, Nieminen MI, Hesse M, He T, Baribault H, Magin TM, Omary MB, Eriksson JE Hepatology View on publisher's site

A1 Journal article (refereed) Human inhibitor of apoptosis protein (IAP) survivin participates in regulation of chromosome segregation and mitotic exit (2001) Kallio MJ, Nieminen M, Eriksson JE FASEB Journal View on publisher's site

A1 Journal article (refereed) MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors (2001) Tran, Holmström, Ahonen, Kähäri, Eriksson Journal of Biological Chemistry View on publisher's site

A1 Journal article (refereed) Mitotic reorganization of the intermediate filament protein nestin involves phosphorylation by cdc2 kinase (2001) Sahlgren, Mikhailov, Hellman, Chou, Lendahl, Goldman, Eriksson Journal of Biological Chemistry View on publisher's site

A1 Journal article (refereed) Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1 (2001) Holmberg, Hietakangas, Mikhailov, Rantanen, Kallio, Meinander, Hellman, Morrice, MacKintosh, Morimoto, Eriksson, Sistonen EMBO Journal View on publisher's site

A1 Journal article (refereed) Primary chondrocytes resist hydrostatic pressure-induced stress while primary synovial cells and fibroblasts show modified Hsp70 response (2001) Kaarniranta, Holmberg, Lammi, Eriksson, Sistonen, Helminen Osteoarthritis and Cartilage View on publisher's site

A1 Journal article (refereed) Production and specificity of mono and polyclonal antibodies against microcystins conjugated through N-methyldehydroalanine (2001) Mikhailov, Härmälä-Braskén, Meriluoto, Sorokina, Dietrich, Eriksson Toxicon

A1 Journal article (refereed) Production and specificity of monoclonal antibodies against nodularin conjugated through N-methyldehydrobutyrine (2001) Mikhailov, Härmälä-Braskén, Polosukhina, Hanski, Wahlsten, Sivonen, Eriksson Toxicon View on publisher's site

A1 Journal article (refereed) The expression of intermediate filament protein nestin as related to vimentin and desmin in regenerating skeletal muscle (2001) Vaittinen, Lukka, Sahlgren, Hurme, Rantanen, Lendahl, Eriksson, Kalimo Journal of Neuropathology and Experimental Neurology

A1 Journal article (refereed) Differences in spindle association of the mitotic checkpoint protein Mad2 in mammalian spermatogenesis and oogenesis (2000) Kallio M, Eriksson JE, Gorbsky GJ Developmental Biology View on publisher's site

A1 Journal article (refereed) Effector caspases are dispensable for the early nuclear morphological changes during chemical-induced apoptosis (2000) Johnson VL, Ko SC, Holmström TH, Eriksson JE, Chow SC Journal of Cell Science

A1 Journal article (refereed) MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly (2000) Holmström, Schmitz, Söderström, Poukkula, Johnson, Chow, Krammer, Eriksson EMBO Journal View on publisher's site

A1 Journal article (refereed) Microcystin-LR toxicodynamics, induced pathology, and immunohistochemical localization in livers of blue-green algae exposed rainbow trout (oncorhynchus mykiss) (2000) Fischer, Hitzfeld, Tencalla, Eriksson, Mikhailov, Dietrich Toxicological Sciences View on publisher's site

A2 Review article, Literature review, Systematic review Phosphorylation-Based signaling in Fas receptor-mediated apoptosis (2000) Holmström, Eriksson Critical Reviews in Immunology

A1 Journal article (refereed) Protein synthesis is required for stabilization of hsp70 mRNA upon exposure to both hydrostatic pressurization and elevated temperature (2000) Kaarniranta, Holmberg, Helminen, Eriksson, Sistonen, Lammi FEBS Letters

A1 Journal article (refereed) Quantitative analysis of the self-assembly strategies of intermediate filaments from tetrameric vimentin (2000) Czeizler E, Mizera A, Czeizler E, Back RJ, Eriksson JE, Petre I IEEE/ACM Transactions on Computational Biology and Bioinformatics View on publisher's site

A1 Journal article (refereed) Inhibition of mitogen-activated kinase signaling sensitizes HeLa cells to Fas receptor-mediated apoptosis (1999) Holmström TH, Tran SE, Johnson VL, Ahn NG, Chow SC, Eriksson JE Molecular and Cellular Biology

A1 Journal article (refereed) Intermediate filament protein partnership in astrocytes (1999) Eliasson, Sahlgren, Berthold, Stakeberg, Celis, Betsholtz, Eriksson, Pekny Journal of Biological Chemistry

A1 Journal article (refereed) Mitotic aberrations induced by carbaryl reflect tyrosine kinase inhibition with coincident up-regulation of serine/threonine protein phosphatase activity: implications for coordination of karyokinesis and cytokinesis (1999) Renglin, Härmälä-Brasken, Eriksson, Onfelt Mutagenesis View on publisher's site

A1 Journal article (refereed) Specific and innervation-regulated expression of the intermediate filament protein nestin at neuromuscular and myotendinous junctions in skeletal muscle (1999) Vaittinen, Lukka, Sahlgren, Rantanen, Hurme, Lendahl, Eriksson, Kalimo American Journal of Pathology View on publisher's site

A1 Journal article (refereed) Toxins affecting cell signalling and alteration of cytoskeletal structure (1999) Toivola, Eriksson Toxicology in Vitro

A1 Journal article (refereed) Amphiphile-induced phosphatidylserine exposure in human erythrocytes (1998) Hägerstrand, Holmström, Bobrowska-Hägerstrand, Eriksson, Isomaa Molecular Membrane Biology

A1 Journal article (refereed) Conventional and novel PKC isoenzymes modify the heat-induced stress response but are not activated by heat shock (1998) Holmberg, Roos, Lord, Eriksson, Sistonen Journal of Cell Science

A1 Journal article (refereed) Enhancement of fibroblast collagenase-1 (MMP-1) gene expression by tumor promoter okadaic acid is mediated by stress-activated protein kinases Jun N-terminal kinase and p38 (1998) Westermarck J, Holmström T, Ahonen M, Eriksson JE, Kähäri VM Matrix Biology

A1 Journal article (refereed) Enhancement of fibroblast collagenase (matrix metalloproteinase-1) gene expression by ceramide is mediated by extracellular signal-regulated and stress-activated protein kinase pathways (1998) Reunanen N, Westermarck J, Häkkinen L, Holmström TH, Elo I, Eriksson JE, Kähäri VM Journal of Biological Chemistry

A1 Journal article (refereed) Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation (1998) Kaarniranta K, Elo M, Sironen R, Lammi MJ, Goldring MB, Eriksson JE, Sistonen L, Helminen HJ Proceedings of the National Academy of Sciences

A1 Journal article (refereed) Protein phosphatase inhibition in normal and keratin 8/18 assembly-incompetent mouse strains supports a functional role of keratin intermediate filaments in preserving hepatocyte integrity (1998) Toivola, Omary, Ku, Peltola, Baribault, Eriksson Hepatology View on publisher's site

A1 Journal article (refereed) Strategies to assess phosphoprotein phosphatase and protein kinase-mediated regulation of the cytoskeleton (1998) Eriksson, Toivola, Sahlgren, Mikhailov, Härmälä-Braskén Methods in Enzymology View on publisher's site

A1 Journal article (refereed) Suppression of Fas/APO-1-mediated apoptosis by mitogen-activated kinase signaling (1998) Holmström, Chow, Elo, Coffey, Orrenius, Sistonen, Eriksson Journal of Immunology

A1 Journal article (refereed) Protein phosphatases maintain the organization and structural interactions of hepatic keratin intermediate filaments (1997) Toivola, Goldman, Garrod, Eriksson Journal of Cell Science

A1 Journal article (refereed) The intermediate filament protein nestin occurs transiently in differentiating testis of rat and mouse (1997) Fröjdman, Pelliniemi, Lendahl, Virtanen, Eriksson Differentiation View on publisher's site

A1 Journal article (refereed) The phorbol ester 12-O-tetradecanoylphorbol 13-acetate enhances the heat-induced stress response (1997) Holmberg, Leppä, Eriksson, Sistonen Journal of Biological Chemistry

A1 Journal article (refereed) Thioredoxin is transcriptionally induced upon activation of heat shock factor 2 (1997) Leppä, Pirkkala, Chow, Eriksson, Sistonen Journal of Biological Chemistry

A1 Journal article (refereed) Choosing analytical strategy for microcystins (1996) Jussi Meriluoto, Ann-Sofi Härmälä-Braskén, John Eriksson, Diana Toivola, Tore Lindholm Phycologia View on publisher's site

A1 Journal article (refereed) Chromatin condensation during apoptosis requires ATP (1996) Kass, Eriksson, Weis, Orrenius, Chow Biochemical Journal

A1 Journal article (refereed) Lamin and beta-tubulin fragmentation precede chromatin degradation in glutamate-induced neuronal apoptosis (1996) Ankarcrona, Zhivotovsky, Holmström, Diana, Eriksson, Orrenius, Nicotera NeuroReport

A1 Journal article (refereed) Solution structure of nodularin. An inhibitor of serine/threonine-specific protein phosphatases (1996) Annila, Lehtimäki, Mattila, Eriksson, Sivonen, Rantala, Drakenberg Journal of Biological Chemistry

A1 Journal article (refereed) Alterations in microtubules, intermediate filaments, and microfilaments induced by microcystin-LR in cultured cells (1995) Wickstrom, Khan, Haschek, Wyman, Eriksson, Schaeffer, Beasley Toxicologic Pathology

A1 Journal article (refereed) Involvement of multiple proteases during Fas-mediated apoptosis in T lymphocytes (1995) Chow, Weis, Kass, Holmström, Eriksson, Orrenius FEBS Letters

A1 Journal article (refereed) PHOSPHORYLATION-MEDIATED SIGNALING MECHANISMS AFFECT THE DNA-BINDING ACTIVITY OF HEAT-SHOCK TRANSCRIPTION FACTOR-1 IN K562 CELLS (1995) HOLMBERG CI, ERIKSSON JE, SISTONEN L Molecular Biology of the Cell

A1 Journal article (refereed) IDENTIFICATION OF PROTEIN PHOSPHATASE 2A AS THE PRIMARY TARGET FOR MICROCYSTIN-1R IN RAT-LIVER HOMOGENATES (1994) TOIVOLA DM, ERIKSSON JE, BRAUTIGAN DL FEBS Letters View on publisher's site

A1 Journal article (refereed) Identification of protein phosphatase 2A as the primary target for microcystin-LR in rat liver homogenates (1994) Toivola DM, Eriksson JE, Brautigan DL FEBS Letters

A4 Conference proceedings Testing of Toxicity in Cyanobacteria by Cellular Assays (1994) J. E. Eriksson, D. M. Toivola, M. Reinikainen, C. M. I. Råbergh, J. A. O. Meriluoto Woodhead Publishing Limited

A1 Journal article (refereed) Uptake of taurocholic acid and cholic acid in isolated hepatocytes from rainbow trout (1994) Råbergh, Ziegler, Isomaa, Lipsky, Eriksson AJP - Gastrointestinal and Liver Physiology

A1 Journal article (refereed) Cytoskeletal integrity in interphase cells requires protein phosphatase activity (1992) Eriksson, Brautigan, Vallee, Olmsted, Fujiki, Goldman Proceedings of the National Academy of Sciences

A2 Review article, Literature review, Systematic review Intermediate filament dynamics (1992) Eriksson JE, Opal P, Goldman RD Current Opinion in Cell Biology

A1 Journal article (refereed) Computer modelling of the 3-dimensional structures of the cyanobacterial hepatotoxins microcystin-LR and nodularin (1991) Lanaras, Cook, Eriksson, Meriluoto, Hotokka Toxicon

A1 Journal article (refereed) MORPHOLOGICAL CHANGES AND CYTOTOXICITY IN ISOLATED HEPATOCYTES (1991) TOIVOLA D, ERIKSSON JE Alternatives to Laboratory Animals

A1 Journal article (refereed) Vimentin is hyperphosphorylated in primary human fibroblasts treated with okadaic acid (1991) Yatsunami, Fujiki, Suganuma, Yoshizawa, Eriksson, Olson, Goldman Biochemical and Biophysical Research Communications View on publisher's site

A1 Journal article (refereed) Hepatocellular uptake of 3H-dihydromicrocystin-LR, a cyclic peptide toxin (1990) Eriksson JE, Grönberg L, Nygård L, Slotte JP, Meriluoto JA BBA - Biomembranes

A1 Journal article (refereed) Hepatocyte deformation induced by cyanobacterial toxins reflects inhibition of protein phosphatases (1990) Eriksson JE, Toivola D, Meriluoto JA, Karaki H, Han YG, Hartshorne D Biochemical and Biophysical Research Communications

A1 Journal article (refereed) Internal surface reversed-phase high-performance liquid chromatographic separation of the cyanobacterial peptide toxins microcystin-LA, -LR, -YR, -RR and nodularin (1990) Meriluoto, Eriksson, Harada, Dahlem, Sivonen, Carmichael Journal of Chromatography A

A1 Journal article (refereed) Structure of a hepatotoxic pentapeptide from the cyanobacterium Nodularia spumigena (1990) Sandström, Glemarec, Meriluoto, Eriksson, Chattopadhyaya Toxicon

A1 Journal article (refereed) Synthesis, organotropism and hepatocellular uptake of two tritium-labeled epimers of dihydromicrocystin-LR, a cyanobacterial peptide toxin analog (1990) Meriluoto, Nygård, Dahlem, Eriksson Toxicon View on publisher's site

A1 Journal article (refereed) Rapid microfilament reorganization induced in isolated rat hepatocytes by microcystin-LR, a cyclic peptide toxin (1989) Eriksson, Paatero, Meriluoto, Codd, Kass, Nicotera, Orrenius Experimental Cell Research

A1 Journal article (refereed) Structure and toxicity of a peptide hepatotoxin from the cyanobacterium Oscillatoria agardhii (1989) Meriluoto, Sandström, Eriksson, Remaud, Craig, Chattopadhyaya Toxicon

A1 Journal article (refereed) A comparison of toxins isolated from the cyanobacteria Oscillatoria agardhii and Microcystis aeruginosa (1988) Eriksson, Meriluoto, Kujari, Skulberg Comparative Biochemistry and Physiology - Part C: Comparative Pharmacology and Toxicology View on publisher's site

A1 Journal article (refereed) Preliminary characterization of a toxin isolated from the cyanobacterium Nodularia spumigena (1988) Eriksson, Meriluoto, Kujari, Österlund, Fagerlund, Hällbom Toxicon View on publisher's site

A1 Journal article (refereed) Rapid analysis of peptide toxins in cyanobacteria (1988) Meriluoto, Eriksson Journal of Chromatography A

A1 Journal article (refereed) Cell selective cytotoxicity of a peptide toxin from the cyanobacterium Microcystis aeruginosa (1987) Eriksson, Hägerstrand, Isomaa BBA - Biochimica et Biophysica Acta

Other publications

B1 Non-refereed journal articles The VIII International Congress on Stress Proteins in Biology and Medicine: täynnä henkeä (2018) Cristina Bonorino, Lea Sistonen, John Eriksson, Valérie Mezger, Gabriella Santoro, Lawrence E. Hightower Cell Stress and Chaperones View on publisher's site

D4 Published development or research report or study Undersökning av förekomsten av toxiska blågrönalger i Långsjön och Markusbölefjärden (1989) Diana Toivola, Jussi Meriluoto, John Eriksson

D4 Published development or research report or study Förekomsten av toxiska blågrönalger i Åländska insjöar (1988) Diana Toivola, John Eriksson, Jussi Meriluoto

Other Research Activities