PhD

Md Abdullah Sazzad

Project researcher, Biochemistry
Email: m.sazzad@abo.fi


Biography

Md Abdullah Al Sazzad is currently a Post-doctoral researcher working in the Laboratory of Lipid and Membrane Biochemistry at Åbo Akademi Univeristy. He received his PhD in 2017. His PhD thesis project has taken place during October, 2013 - December, 2017 in Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, Finland. Sazzad completed MSc in Bioinformatics from University of Turku in 2013 and received his BSc in Biotechnology and Genetic Engineering from Khulna University, Bangladesh. He has expertise in Analytical Biochemistry, Biophysics, and Bioinformatics. His research is focused on the interplay between lipids in membranes and how lipid structure and interactions affect the lateral heterogeneity of membranes.


Professional interests

Ceramides belong to an
important class of sphingolipids and play key role in different biological
processes such as cell signaling, proliferation, differentiation and apoptosis.
Particularly, the role of ceramides in apoptosis has received special attention
in recent years. The objective of his research
project is to understand how favorably (or unfavorably) ceramides associate with
different phospholipids and with other sphingolipids thought to be present in
lipid domains in cell membranes,
which may have distinct effects on cell physiology.


Research Areas


Keywords

Ceramides, Cholesterol, LIPIDS, Membranes, sphingolipids


Peer-reviewed publications

A1 Journal article (refereed)
Lateral Segregation of Palmitoyl Ceramide-1-Phosphate in Simple and Complex Bilayers (2019)
Md. Abdullah Al Sazzad, Tomokazu Yasuda, Thomas K.M. Nyholm, J. Peter Slotte
Biophysical Journal
Langmuir
View on publisher's site
A1 Journal article (refereed)
Natural Ceramides and Lysophospholipids Cosegregate in Fluid Phosphatidylcholine Bilayers (2019)
Md. Abdullah Al Sazzad, Anna Möuts, Juan Palacios-Ortega, Kai-Lan Lin, Thomas K. M. Nyholm, J. PeterSlotte
Biophysical Journal
Biophysical Journal
View on publisher's site
A1 Journal article (refereed)
Sphingomyelin Stereoisomers Reveal That Homophilic Interactions Cause Nanodomain Formation. (2018)
Yano Y, Hanashima S, Yasuda T, Tsuchikawa H, Matsumori N, Kinoshita M, Al Sazzad MA, Slotte JP, Murata M
Biophysical Journal
Biophysical Journal
View on publisher's site
A1 Journal article (refereed)
Bilayer Interactions among Unsaturated Phospholipids, Sterols, and Ceramide (2017)
Slotte JP, Yasuda T, Engberg O, Al Sazzad MA, Hautala V, Nyholm TKM, Murata M
Biophysical Journal
View on publisher's site
A1 Journal article (refereed)
The Long-Chain Sphingoid Base of Ceramides Determines Their Propensity for Lateral Segregation (2017)
Md Abdullah Al Sazzad, Tomokazu Yasuda, Michio Murata, J Peter Slotte
Biophysical Journal
View on publisher's site
A1 Journal article (refereed)
Regulation of Sticholysin II-Induced Pore Formation by Lipid Bilayer Composition, Phase State, and Interfacial Properties
(2016)
Palacios-Ortega J, Garcia-Linares S, Åstrand M, Al Sazzad MA, Gavilanes JG, Martinez-del-Pozo A, Slotte JP
View on publisher's site
A1 Journal article (refereed)
The Influence of Hydrogen Bonding on Sphingomyelin/Colipid Interactions in Bilayer Membranes (2016)
Yasuda T, Al Sazzad MA, Jäntti NZ, Pentikäinen OT, Slotte JP

Last updated on 2020-03-07 at 02:20